close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH45956.1COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: tye:THEYE_A0591 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285445; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3. (588 aa)    
Predicted Functional Partners:
AEH45955.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900:IPR017896; KEGG: tpe:Tpen_1816 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; IMG reference gene:2505285444; PFAM: 4Fe-4S binding domain.
 
   0.936
AEH45958.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: cpo:COPRO5265_0137 tungsten-containing aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Tungsten-containing aldehyde ferredoxin oxidoreductase; IMG reference gene:2505285447; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
  
  
 
0.925
AEH45957.1
KEGG: apo:Arcpr_1635 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285446.
       0.779
AEH44518.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
     0.775
AEH45679.1
Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: dps:DP1772 polyferredoxins; SPTR: Related to polyferredoxins; IMG reference gene:2505285150; PFAM: 4Fe-4S binding domain.
   
 
 0.623
AEH46070.1
Hypothetical protein; InterPro IPR017900:IPR017896; KEGG: dap:Dacet_0088 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; IMG reference gene:2505285561; TIGRFAM: ferredoxin-type protein NapF; MauM/NapG family ferredoxin-type protein.
   
 
 0.587
AEH44201.1
ABC transporter, periplasmic substrate-binding protein; COGs: COG2998 ABC-type tungstate transport system permease component; KEGG: aco:Amico_1561 ABC transporter, periplasmic substrate-binding protein; SPTR: Tungstate ABC transporter, tungstate-binding protein; IMG reference gene:2505283606.
 
   
 0.580
AEH45954.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006439; KEGG: phe:Phep_1975 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2505285443; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E.
       0.553
AEH44961.1
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR017896; KEGG: dma:DMR_26720 molybdopterin oxidoreductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; IMG reference gene:2505284400; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductas [...]
  
 
 0.552
AEH44415.1
NIL domain protein; InterPro IPR018449:IPR017896:IPR017900; KEGG: sat:SYN_00800 ferridoxin; PFAM: NIL domain; SPTR: Ferridoxin; IMG reference gene:2505283827; PFAM: 4Fe-4S binding domain; NIL domain.
  
   0.525
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.