Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rlmHProtein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa)    
Predicted Functional Partners:
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.832
AEH45964.1
Uncharacterized protein family UPF0066; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: tye:THEYE_A1086 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: Putative uncharacterized protein; IMG reference gene:2505285453; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: putative methyltransferase, YaeB/AF_0241 family.
  
    0.781
AEH45966.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dal:Dalk_2812 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2505285455; PFAM: Glycosyl transferase family 2.
       0.773
AEH45967.1
Type IV pilus assembly PilZ; InterPro IPR009875; KEGG: hoh:Hoch_6704 response regulator receiver modulated PilZ sensor protein; PFAM: type IV pilus assembly PilZ; SPTR: Response regulator receiver modulated PilZ sensor protein; IMG reference gene:2505285456; PFAM: PilZ domain.
       0.724
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.533
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.525
rsmI
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.522
AEH45583.1
Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
  
     0.480
AEH45963.1
KEGG: dol:Dole_1955 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285452.
       0.448
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
   
    0.443
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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