Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEH46001.1InterPro IPR000620; KEGG: dat:HRM2_13600 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2505285490; PFAM: EamA-like transporter family. (301 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.752
AEH45993.1
Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: dak:DaAHT2_1197 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; IMG reference gene:2505285482; PFAM: Predicted permease; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.467
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.465
AEH45999.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: aae:aq_1899 dolichol-phosphate mannosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Dolichol-phosphate mannosyltransferase; IMG reference gene:2505285488; PFAM: Glycosyl transferase family 2.
  
 
 0.438
AEH45283.1
Ion transport 2 domain protein; COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646:IPR013099; KEGG: dal:Dalk_3538 ion transport 2 domain protein; PFAM: Ion transport 2 domain protein; pentapeptide repeat protein; SPTR: Ion transport 2 domain protein; IMG reference gene:2505284732; PFAM: Pentapeptide repeats (8 copies); Ion channel.
   
 
 0.434
AEH45995.1
COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: sfu:Sfum_3063 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; IMG reference gene:2505285484; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.
   
   0.433
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861:IPR001917; KEGG: dak:DaAHT2_2672 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; IMG reference gene:2505285486; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.425
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.413
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.405
AEH46000.1
Hypothetical protein; InterPro IPR005242; KEGG: min:Minf_2171 hypothetical protein; SPTR: Uncharacterized conserved membrane protein; IMG reference gene:2505285489; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
  
    0.400
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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