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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH46009.1Extracellular solute-binding protein family 1; COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR001188:IPR006059; KEGG: ddf:DEFDS_1582 spermidine/putrescine ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Spermidine/putrescine-binding periplasmic protein; IMG reference gene:2505285498; PFAM: Bacterial extracellular solute-binding protein. (353 aa)    
Predicted Functional Partners:
AEH46006.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: ddf:DEFDS_1579 spermidine/putrescine ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type spermidine/putrescine transport system, permease component II; IMG reference gene:2505285495; PFAM: Binding-protein-dependent transport system inner membrane component.
 
 0.999
AEH46007.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG1176 ABC-type spermidine/putrescine transport system permease component I; InterPro IPR000515; KEGG: ant:Arnit_1316 binding-protein-dependent transporter inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type spermidine/putrescine transport system, permease component I; IMG reference gene:2505285496; PFAM: Binding-protein-dependent transport system inner membrane component.
 
 
 0.997
AEH46008.1
ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611:IPR017871; KEGG: ddf:DEFDS_1581 spermidine/putrescine ABC transporter ATP-binding protein; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: Spermidine/putrescine ABC transporter, ATP-binding protein (PotA); IMG reference gene:2505285497; PFAM: ABC transporter; TOBE domain.
 
 
 0.993
AEH44368.1
ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR017871:IPR003593; KEGG: pca:Pcar_1735 ATP-binding component of transport system for maltose; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: ATP-binding component of transport system for maltose; IMG reference gene:2505283775; PFAM: ABC transporter; TOBE domain.
 
  
 0.879
AEH45728.1
Cupin 2 conserved barrel domain protein; InterPro IPR001387:IPR013096; KEGG: gur:Gura_0980 XRE family transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2505285202; PFAM: Cupin domain; Helix-turn-helix.
 
   
 0.666
AEH46005.1
Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: rca:Rcas_1244 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; IMG reference gene:2505285494; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
       0.605
AEH44554.1
ABC transporter related protein; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593:IPR017871; KEGG: ant:Arnit_1355 ABC transporter-like protein; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: ABC transporter related protein; IMG reference gene:2505283970; PFAM: ABC transporter; TOBE domain.
 
   
 0.575
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.548
AEH46004.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.468
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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