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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH46033.1KEGG: pth:PTH_1005 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2505285522; PFAM: Methylene-tetrahydrofolate reductase C terminal. (225 aa)    
Predicted Functional Partners:
AEH46032.1
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR019734:IPR003171:IPR016041:IPR013026; KEGG: dak:DaAHT2_0826 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; methylenetetrahydrofolate reductase; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285521; PFAM: Methylenetetrahydrofolate reductase; CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit.
 
  
 0.976
AEH46031.1
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: dak:DaAHT2_0825 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; IMG reference gene:2505285520; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit.
 
   
 0.966
AEH46030.1
CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041:IPR016218; KEGG: dak:DaAHT2_0824 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; IMG reference gene:2505285519; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
   
 0.919
AEH46038.1
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR004137:IPR010047; KEGG: adg:Adeg_0335 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; IMG reference gene:2505285527; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
 
   
 0.898
AEH46042.1
InterPro IPR017909:IPR006311; KEGG: dak:DaAHT2_0012 chain A, iron Centre cytochrome c protein; SPTR: Chain A, iron Centre cytochrome c protein; IMG reference gene:2505285531.
  
 
 0.850
AEH46034.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: adg:Adeg_0343 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; IMG reference gene:2505285523; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
     0.847
AEH46035.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017896; KEGG: dak:DaAHT2_1634 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; IMG reference gene:2505285524.
       0.843
AEH46027.1
Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: dak:DaAHT2_1991 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: Dihydropteroate synthase DHPS; IMG reference gene:2505285516; PFAM: Pterin binding enzyme.
 
   
 0.827
AEH46036.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dak:DaAHT2_0821 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285525; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
       0.805
AEH45313.1
InterPro IPR007202; KEGG: dak:DaAHT2_0716 Fe-S cluster domain protein; PFAM: Fe-S cluster domain protein; SPTR: Putative Fe-S cluster; IMG reference gene:2505284768; PFAM: Putative Fe-S cluster.
 
   
 0.782
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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