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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEH46046.1COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR002332:IPR017918; KEGG: pmx:PERMA_1585 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505285535; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.993
AEH44087.1
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: slp:Slip_2119 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; IMG reference gene:2505283485; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
 0.982
AEH45358.1
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR018047; KEGG: drt:Dret_2267 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; IMG reference gene:2505284814; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter.
 
 
 0.975
AEH44088.1
COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187:IPR017918; KEGG: dth:DICTH_0174 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; IMG reference gene:2505283486; PFAM: Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
  
  
 
0.904
AEH46044.1
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: dal:Dalk_5100 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; IMG reference gene:2505285533; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
  
 0.737
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.605
AEH44973.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR003661:IPR003594:IPR001789:IPR004358:IPR 000014:IPR005467; KEGG: ddf:DEFDS_0784 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; IMG reference gene:2505284412; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator re [...]
  
 
 0.596
AEH45731.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: drm:Dred_1311 sensory histidine kinase AtoS; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine-protein kinase atoS; IMG reference gene:2505285206; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   
 
 0.574
AEH43991.1
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: mrb:Mrub_0165 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylation/Crystallin J1; IMG reference gene:2505283388; PFAM: ADP-ribosylglycohydrolase; TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase.
    
 
 0.561
AEH46043.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sul:SYO3AOP1_1193 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; IMG reference gene:2505285532; PFAM: Methyltransferase domain.
       0.519
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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