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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH46060.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: dak:DaAHT2_0099 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; IMG reference gene:2505285551; PFAM: Aminotransferase class I and II. (395 aa)    
Predicted Functional Partners:
AEH44803.1
COGs: COG0077 Prephenate dehydratase; InterProIPR018528:IPR020822:IPR001086:IPR002912:IPR 008242:IPR002701; KEGG: dak:DaAHT2_0619 prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase:Chorismate mutase:Amino acid-binding ACT; IMG reference gene:2505284236; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
 
 0.936
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: dak:DaAHT2_2212 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; IMG reference gene:2505283851; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.915
AEH44685.1
GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: aae:aq_1359 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2505284104; PFAM: Acetyltransferase (GNAT) family.
  
  
  0.915
AEH45243.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; IMG reference gene:2505284692; PFAM: Aminotransferase class I and II.
  
  
 
0.914
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.912
AEH43928.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR005958:IPR004838; KEGG: aba:Acid345_1458 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; TIGRFAM: tyrosine/nicotianamine aminotransferase; IMG reference gene:2505283325; PFAM: Aminotransferase class I and II; TIGRFAM: tyrosine aminotransferase, eukaryotic; tyrosine/nicotianamine aminotransferases.
  
  
 
0.909
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.909
AEH44813.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR004455:IPR003099; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; SPTR: Prephenate dehydrogenase; IMG reference gene:2505284246; PFAM: Prephenate dehydrogenase.
  
 
 0.907
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.905
AEH44373.1
Fumarate lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362:IPR018951:IPR020557; KEGG: mta:Moth_1273 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarase; IMG reference gene:2505283780; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase.
     
 0.904
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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