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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
AEH46068.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dba:Dbac_2095 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; IMG reference gene:2505285559; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C [...] (231 aa)    
Predicted Functional Partners:
AEH44277.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: drt:Dret_0468 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensory box histidine kinase PhoR; IMG reference gene:2505283684; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
  0.987
AEH46067.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467:IPR009056; KEGG: dba:Dbac_2092 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; IMG reference gene:2505285558; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, [...]
 
 0.969
AEH45062.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013656:IPR013767:IPR005467:IPR000700; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; response regulator r [...]
 
 
 0.922
AEH44144.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR013655:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700; KEGG: dak:DaAHT2_2564 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hyb [...]
 
 0.913
AEH45478.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 005467:IPR000700:IPR013767; KEGG: sfu:Sfum_2763 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505284940; PFAM: Histidine kinase-, DNA gyrase B-, and HSP [...]
 
 
 0.898
AEH44786.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR003594:IPR 004358; KEGG: cts:Ctha_2235 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid histidine kinase; IMG reference gene:2505284216; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
 
 
 0.894
AEH45521.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR001789:IPR005467; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: PAS sensor protein; IMG reference gene:2505284984; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain.
 
 
 0.894
AEH44443.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: sus:Acid_7874 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2505283856; PFAM: HAMP domain; Histidine kinase-, DN [...]
 
 0.865
AEH44293.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 004358:IPR005467:IPR000700; KEGG: tye:THEYE_A0125 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor histidine kinase; TIGRFAM: PAS sensor protein; IMG reference gene:2505283700; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like [...]
 
 
 0.861
AEH44013.1
Histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358:IPR003594:IPR005467; KEGG: dak:DaAHT2_2152 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensory box histidine kinase/response regulator; IMG reference gene:2505283411; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
   0.855
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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