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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH46070.1Hypothetical protein; InterPro IPR017900:IPR017896; KEGG: dap:Dacet_0088 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; manually curated; IMG reference gene:2505285561; TIGRFAM: ferredoxin-type protein NapF; MauM/NapG family ferredoxin-type protein. (190 aa)    
Predicted Functional Partners:
AEH44377.1
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR004108:IPR003149:IPR017896:IPR 017900; KEGG: hor:Hore_06330 NADH dehydrogenase (ubiquinone) 75 kDa subunit; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: NADH dehydrogenase (Ubiquinone) 75 kDa subunit; TIGRFAM: hydrogenase, Fe-only; IMG reference gene:2505283784; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only.
  
 
 0.992
AEH46069.1
Periplasmic nitrate reductase NapH; COGs: COG0348 Polyferredoxin; InterPro IPR017900:IPR000463:IPR017896; KEGG: ddf:DEFDS_1823 periplasmic nitrate reductase NapH; SPTR: Periplasmic nitrate reductase NapH; IMG reference gene:2505285560; TIGRFAM: ferredoxin-type protein, NapH/MauN family.
    0.976
AEH46025.1
Formate dehydrogenase, alpha subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR000759:IPR001041:IPR013027:IPR006963:IPR 006656:IPR006657:IPR018247:IPR017900:IPR006655:IPR017896:I PR006478; KEGG: dak:DaAHT2_0823 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; selenocysteine- [...]
 
 
 0.951
napA
Molybdopterin oxidoreductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
 
   
 0.903
AEH46073.1
Multiheme C-type cytochrome; InterPro IPR011031; KEGG: ddf:DEFDS_1819 multiheme C-type cytochrome; SPTR: Multiheme c-type cytochrome; IMG reference gene:2505285564; PFAM: Class III cytochrome C family.
 
     0.888
AEH45676.1
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311:IPR017909:IPR006655:IPR006963:IPR 006656:IPR006657; KEGG: ddf:DEFDS_1331 formate dehydrogenase subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Formate dehydrogenase, alpha subunit; manually curated; selenocysteine-containing protein; IMG reference gene:2505285147; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxi [...]
 
 
 0.831
napD
NapD family protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
     
 0.826
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.652
AEH45551.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: drt:Dret_1785 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; IMG reference gene:2505285016.
 
    0.600
AEH44720.1
Hypothetical protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896:IPR017900; KEGG: gsu:GSU0729 iron-sulfur cluster-binding protein; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2505284145.
 
    0.596
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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