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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH46075.1KEGG: nam:NAMH_1746 transporter gate domain protein; SPTR: Transporter gate domain protein; IMG reference gene:2505285566; PFAM: Nucleoside recognition. (279 aa)    
Predicted Functional Partners:
AEH45137.1
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481:IPR007167; KEGG: dal:Dalk_1640 ferric uptake regulator, Fur family; PFAM: FeoA family protein; ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; IMG reference gene:2505284583; PFAM: FeoA domain; Ferric uptake regulator family; Belongs to the Fur family.
  
  
 0.801
AEH46074.1
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
       0.768
AEH44237.1
FeoA family protein; COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: pru:PRU_0867 ferrous iron transport protein B; PFAM: FeoA family protein; SPTR: Ferrous iron transport protein B; IMG reference gene:2505283643; PFAM: FeoA domain.
  
  
 0.626
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
   
 0.545
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.437
AEH44963.1
Metallophosphoesterase; InterPro IPR004843:IPR004365; KEGG: mif:Metin_0769 metallophosphoesterase; PFAM: metallophosphoesterase; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Putative uncharacterized protein; IMG reference gene:2505284402; PFAM: Calcineurin-like phosphoesterase.
  
     0.417
Your Current Organism:
Thermodesulfatator indicus
NCBI taxonomy Id: 667014
Other names: T. indicus DSM 15286, Thermodesulfatator indicus CIR29812, Thermodesulfatator indicus DSM 15286, Thermodesulfatator indicus str. DSM 15286, Thermodesulfatator indicus strain DSM 15286, Thermodesulfobacterium sp. CIR29812
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