STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (674 aa)    
Predicted Functional Partners:
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 0.991
ADY36002.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.987
ADY37432.1
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.987
ADY36154.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014001:IPR001650:IPR004589:IPR011545:IPR000212; KEGG: dsy:DSY0682 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA helicase, UvrD/REP type; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: Helicase conserved C-terminal domain; UvrD/REP helicase; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
  
 
 0.702
ADY35372.1
Outer membrane assembly lipoprotein YfiO; COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689; KEGG: bvu:BVU_3041 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO.
       0.698
ADY38058.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: bvu:BVU_3538 putative helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative uncharacterized protein; PFAM: UvrD/REP helicase.
 
 
 0.693
ADY35371.1
KEGG: bvu:BVU_3042 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: RNA polymerase Rpb6.
     
 0.680
ADY35744.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: bth:BT_2999 helicase IV; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative uncharacterized protein; PFAM: UvrD/REP helicase.
  
 
 0.616
ADY35370.1
KEGG: bvu:BVU_3043 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.588
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.563
Your Current Organism:
Bacteroides salanitronis
NCBI taxonomy Id: 667015
Other names: B. salanitronis DSM 18170, Bacteroides salanitronis BL78, Bacteroides salanitronis DSM 18170, Bacteroides salanitronis JCM 13657, Bacteroides salanitronis str. DSM 18170, Bacteroides salanitronis strain DSM 18170
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