STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (274 aa)    
Predicted Functional Partners:
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.844
EEX51267.1
Hypothetical protein.
       0.773
fkpB2
Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG0545; Pfam: PF01346,PF00254; InterPro: IPR001179.
    
 0.695
fkpB
Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG0545; Pfam: PF01346,PF00254; InterPro: IPR000774.
    
 0.695
holA
DNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790.
 
     0.652
surA
PPIC-type PPIASE domain protein; COG: COG0760; Pfam: PF09312,PF00639; InterPro: IPR000297.
 
 
 0.652
YbfF
Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073.
    
  0.651
menH
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
    
  0.651
sspB
Stringent starvation protein B; COG: COG2969; Pfam: PF04386; InterPro: IPR007481.
  
     0.594
hepA
SNF2 family N-terminal domain protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 
 0.576
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.