STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnAGlutamine synthetase, type I; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809. (472 aa)    
Predicted Functional Partners:
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.943
glmS
Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.938
carB
Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family.
  
 
 0.934
carA
Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family.
  
 
 0.932
gdhA
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.929
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.917
arcC
Carbamate kinase; COG: COG0549; Pfam: PF00696; InterPro: IPR003964; Belongs to the carbamate kinase family.
     
 0.912
nrfA
Formate-dependent cytochrome c nitrite reductase, c552 subunit; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
     
 0.902
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
 
 0.872
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.847
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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