STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppiDPPIC-type PPIASE domain protein; COG: COG0760; Pfam: PF00639; InterPro: IPR000297. (625 aa)    
Predicted Functional Partners:
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00676,PF02779; InterPro: IPR011603.
  
 0.909
gor
Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322.
  
 0.860
lpdA
Dihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258.
  
 0.860
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.806
arcB
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594.
  
 0.767
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.765
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.761
gltA
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family.
  
 
 0.734
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.713
frdB
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; COG: COG0479; Pfam: PF00111,PF00037; InterPro: IPR004489; overlaps another CDS with the same product name; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.701
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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