| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argA | argB | HMPREF0621_1712 | HMPREF0621_0289 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.993 |
| argA | argC | HMPREF0621_1712 | HMPREF0621_0290 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.971 |
| argA | argD | HMPREF0621_1712 | HMPREF0621_0319 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; COG: COG4992; Pfam: PF00202; InterPro: IPR004636; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.920 |
| argA | argE | HMPREF0621_1712 | HMPREF0621_0291 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Acetylornithine deacetylase ArgE; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010169. | 0.676 |
| argA | argF | HMPREF0621_1712 | HMPREF0621_0998 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.903 |
| argA | argG | HMPREF0621_1712 | HMPREF0621_1003 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.956 |
| argA | argH | HMPREF0621_1712 | HMPREF0621_0288 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Argininosuccinate lyase; COG: COG0165; Pfam: PF00206; InterPro: IPR009049. | 0.959 |
| argB | argA | HMPREF0621_0289 | HMPREF0621_1712 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | 0.993 |
| argB | argC | HMPREF0621_0289 | HMPREF0621_0290 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argD | HMPREF0621_0289 | HMPREF0621_0319 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; COG: COG4992; Pfam: PF00202; InterPro: IPR004636; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.916 |
| argB | argE | HMPREF0621_0289 | HMPREF0621_0291 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Acetylornithine deacetylase ArgE; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010169. | 0.717 |
| argB | argF | HMPREF0621_0289 | HMPREF0621_0998 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.785 |
| argB | argG | HMPREF0621_0289 | HMPREF0621_1003 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.936 |
| argB | argH | HMPREF0621_0289 | HMPREF0621_0288 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Argininosuccinate lyase; COG: COG0165; Pfam: PF00206; InterPro: IPR009049. | 0.984 |
| argC | argA | HMPREF0621_0290 | HMPREF0621_1712 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | 0.971 |
| argC | argB | HMPREF0621_0290 | HMPREF0621_0289 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
| argC | argD | HMPREF0621_0290 | HMPREF0621_0319 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; COG: COG4992; Pfam: PF00202; InterPro: IPR004636; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.994 |
| argC | argE | HMPREF0621_0290 | HMPREF0621_0291 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Acetylornithine deacetylase ArgE; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010169. | 0.740 |
| argC | argF | HMPREF0621_0290 | HMPREF0621_0998 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.933 |
| argC | argG | HMPREF0621_0290 | HMPREF0621_1003 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 2 subfamily. | 0.927 |