Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahpC | fur | HMPREF0621_1510 | HMPREF0621_0987 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.720 |
| ahpC | groL | HMPREF0621_1510 | HMPREF0621_0547 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.511 |
| ahpC | sodA | HMPREF0621_1510 | HMPREF0621_0490 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.586 |
| ahpC | trxA | HMPREF0621_1510 | HMPREF0621_0404 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.496 |
| ahpC | trxB | HMPREF0621_1510 | HMPREF0621_1689 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.903 |
| dnaJ | fusA | HMPREF0621_0949 | HMPREF0621_0632 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.838 |
| dnaJ | groL | HMPREF0621_0949 | HMPREF0621_0547 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.865 |
| dnaJ | hslU | HMPREF0621_0949 | HMPREF0621_0769 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.888 |
| dnaJ | sodA | HMPREF0621_0949 | HMPREF0621_0490 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Superoxide dismutase [Mn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.851 |
| dnaJ | trxA | HMPREF0621_0949 | HMPREF0621_0404 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.505 |
| dnaJ | trxB | HMPREF0621_0949 | HMPREF0621_1689 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.426 |
| fur | ahpC | HMPREF0621_0987 | HMPREF0621_1510 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | 0.720 |
| fur | trxA | HMPREF0621_0987 | HMPREF0621_0404 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.510 |
| fusA | dnaJ | HMPREF0621_0632 | HMPREF0621_0949 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.838 |
| fusA | groL | HMPREF0621_0632 | HMPREF0621_0547 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.514 |
| fusA | trxA | HMPREF0621_0632 | HMPREF0621_0404 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.552 |
| gor | trxA | HMPREF0621_0049 | HMPREF0621_0404 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.494 |
| gor | trxB | HMPREF0621_0049 | HMPREF0621_1689 | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.464 |
| groL | ahpC | HMPREF0621_0547 | HMPREF0621_1510 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | 0.511 |
| groL | dnaJ | HMPREF0621_0547 | HMPREF0621_0949 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.865 |
page 1 of 3