| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ccmA | ccmB | HMPREF0621_0479 | HMPREF0621_0478 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.999 |
| ccmA | ccmC | HMPREF0621_0479 | HMPREF0621_0477 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.997 |
| ccmA | ccmD | HMPREF0621_0479 | HMPREF0621_0476 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.918 |
| ccmA | ccmE | HMPREF0621_0479 | HMPREF0621_0475 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.963 |
| ccmA | ccmF | HMPREF0621_0479 | HMPREF0621_0474 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c-type biogenesis protein CcmF; COG: COG1138; Pfam: PF01578; InterPro: IPR003568. | 0.931 |
| ccmA | ccmI | HMPREF0621_0479 | HMPREF0621_0471 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c-type biogenesis protein CcmI; COG: COG4235; Pfam: PF07719; InterPro: IPR011990. | 0.910 |
| ccmA | cycL | HMPREF0621_0479 | HMPREF0621_0472 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome C biogenesis protein; Possible subunit of a heme lyase. | 0.948 |
| ccmA | dsbE-2 | HMPREF0621_0479 | HMPREF0621_0473 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | 0.917 |
| ccmA | nrfE | HMPREF0621_0479 | HMPREF0621_0457 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c nitrate reductase biogenesis protein NrfE; COG: COG1138; Pfam: PF01578; InterPro: IPR003568. | 0.774 |
| ccmA | nrfF-2 | HMPREF0621_0479 | HMPREF0621_0455 | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c nitrite reductase, accessory protein NrfF; Possible subunit of a heme lyase. | 0.860 |
| ccmB | ccmA | HMPREF0621_0478 | HMPREF0621_0479 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.999 |
| ccmB | ccmC | HMPREF0621_0478 | HMPREF0621_0477 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.998 |
| ccmB | ccmD | HMPREF0621_0478 | HMPREF0621_0476 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.965 |
| ccmB | ccmE | HMPREF0621_0478 | HMPREF0621_0475 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.977 |
| ccmB | ccmF | HMPREF0621_0478 | HMPREF0621_0474 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmF; COG: COG1138; Pfam: PF01578; InterPro: IPR003568. | 0.950 |
| ccmB | ccmI | HMPREF0621_0478 | HMPREF0621_0471 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis protein CcmI; COG: COG4235; Pfam: PF07719; InterPro: IPR011990. | 0.933 |
| ccmB | cycL | HMPREF0621_0478 | HMPREF0621_0472 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome C biogenesis protein; Possible subunit of a heme lyase. | 0.954 |
| ccmB | dsbE-2 | HMPREF0621_0478 | HMPREF0621_0473 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | 0.948 |
| ccmB | nrfE | HMPREF0621_0478 | HMPREF0621_0457 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c nitrate reductase biogenesis protein NrfE; COG: COG1138; Pfam: PF01578; InterPro: IPR003568. | 0.804 |
| ccmB | nrfF-2 | HMPREF0621_0478 | HMPREF0621_0455 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c nitrite reductase, accessory protein NrfF; Possible subunit of a heme lyase. | 0.861 |