| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FruB | Mlc | HMPREF0621_1914 | HMPREF0621_1388 | Hypothetical protein; 2.7.1.-. | Hypothetical protein. | 0.465 |
| FruB | ptbA | HMPREF0621_1914 | HMPREF0621_1176 | Hypothetical protein; 2.7.1.-. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.702 |
| FruB | treP | HMPREF0621_1914 | HMPREF0621_0485 | Hypothetical protein; 2.7.1.-. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.651 |
| Mlc | FruB | HMPREF0621_1388 | HMPREF0621_1914 | Hypothetical protein. | Hypothetical protein; 2.7.1.-. | 0.465 |
| Mlc | treP | HMPREF0621_1388 | HMPREF0621_0485 | Hypothetical protein. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.759 |
| nagC | treP | HMPREF0621_1627 | HMPREF0621_0485 | ROK family protein; COG: COG1940; Pfam: PF01047,PF00480; InterPro: IPR000600. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.759 |
| nagC2 | scrB | HMPREF0621_1960 | HMPREF0621_1874 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.907 |
| nagC2 | treP | HMPREF0621_1960 | HMPREF0621_0485 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.759 |
| nagK | treP | HMPREF0621_1596 | HMPREF0621_0485 | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.759 |
| nanK | treP | HMPREF0621_0015 | HMPREF0621_0485 | ROK family protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.759 |
| ptbA | FruB | HMPREF0621_1176 | HMPREF0621_1914 | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | Hypothetical protein; 2.7.1.-. | 0.702 |
| ptbA | ptsH | HMPREF0621_1176 | HMPREF0621_1174 | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | Phosphocarrier, HPr family; COG: COG1925; Pfam: PF00381; InterPro: IPR000032. | 0.995 |
| ptbA | scrB | HMPREF0621_1176 | HMPREF0621_1874 | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.472 |
| ptbA | treC | HMPREF0621_1176 | HMPREF0621_0483 | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | Alpha,alpha-phosphotrehalase; COG: COG0366; Pfam: PF00128; InterPro: IPR012769. | 0.914 |
| ptbA | treP | HMPREF0621_1176 | HMPREF0621_0485 | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.999 |
| ptsH | ptbA | HMPREF0621_1174 | HMPREF0621_1176 | Phosphocarrier, HPr family; COG: COG1925; Pfam: PF00381; InterPro: IPR000032. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.995 |
| ptsH | treP | HMPREF0621_1174 | HMPREF0621_0485 | Phosphocarrier, HPr family; COG: COG1925; Pfam: PF00381; InterPro: IPR000032. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.939 |
| scrB | nagC2 | HMPREF0621_1874 | HMPREF0621_1960 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.907 |
| scrB | ptbA | HMPREF0621_1874 | HMPREF0621_1176 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.472 |
| scrB | treC | HMPREF0621_1874 | HMPREF0621_0483 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | Alpha,alpha-phosphotrehalase; COG: COG0366; Pfam: PF00128; InterPro: IPR012769. | 0.598 |