| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hsf2_3 | wcaA | HMPREF0621_0574 | HMPREF0621_0573 | YadA-like domain protein; COG: COG5295; Pfam: PF05662,PF03895; InterPro: IPR005594. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.458 |
| coaD | kdtA | HMPREF0621_0571 | HMPREF0621_0572 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.820 |
| coaD | wcaA | HMPREF0621_0571 | HMPREF0621_0573 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.638 |
| kdtA | coaD | HMPREF0621_0572 | HMPREF0621_0571 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.820 |
| kdtA | lpxK | HMPREF0621_0572 | HMPREF0621_1651 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
| kdtA | rfaF | HMPREF0621_0572 | HMPREF0621_1878 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.945 |
| kdtA | wcaA | HMPREF0621_0572 | HMPREF0621_0573 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.648 |
| lpxK | kdtA | HMPREF0621_1651 | HMPREF0621_0572 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.998 |
| lpxK | rfaF | HMPREF0621_1651 | HMPREF0621_1878 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.407 |
| lpxK | wcaA | HMPREF0621_1651 | HMPREF0621_0573 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.586 |
| rfaD | rfaF | HMPREF0621_0657 | HMPREF0621_1878 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.815 |
| rfaD | waaQ | HMPREF0621_0657 | HMPREF0621_0712 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Heptosyltransferase; COG: COG0859; Pfam: PF01075. | 0.467 |
| rfaD | wcaA | HMPREF0621_0657 | HMPREF0621_0573 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.491 |
| rfaF | kdtA | HMPREF0621_1878 | HMPREF0621_0572 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.945 |
| rfaF | lpxK | HMPREF0621_1878 | HMPREF0621_1651 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.407 |
| rfaF | rfaD | HMPREF0621_1878 | HMPREF0621_0657 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.815 |
| rfaF | waaQ | HMPREF0621_1878 | HMPREF0621_0712 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Heptosyltransferase; COG: COG0859; Pfam: PF01075. | 0.678 |
| rfaF | wcaA | HMPREF0621_1878 | HMPREF0621_0573 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.619 |
| waaQ | rfaD | HMPREF0621_0712 | HMPREF0621_0657 | Heptosyltransferase; COG: COG0859; Pfam: PF01075. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.467 |
| waaQ | rfaF | HMPREF0621_0712 | HMPREF0621_1878 | Heptosyltransferase; COG: COG0859; Pfam: PF01075. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.678 |