STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slyXSlyX family protein; COG: COG2900; Pfam: PF04102; InterPro: IPR007236; Belongs to the SlyX family. (73 aa)    
Predicted Functional Partners:
FabR
Transcriptional regulator, TetR family; COG: COG1309; Pfam: PF00440; InterPro: IPR001647.
 
     0.689
fkpB
Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG0545; Pfam: PF01346,PF00254; InterPro: IPR000774.
     
 0.575
metJ
Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
     0.572
lapA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.561
rseA
Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...]
  
     0.556
YfbV
Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334.
  
     0.546
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.519
sprT
Metallopeptidase, SprT family; COG: COG3091; Pfam: PF03926; InterPro: IPR006640; Belongs to the SprT family.
  
     0.511
plsB
Glycerol-3-phosphate O-acyltransferase; COG: COG2937; Pfam: PF01553; InterPro: IPR002123; Belongs to the GPAT/DAPAT family.
 
     0.474
ftsN
Cell division protein FtsN; Pfam: PF05036; InterPro: IPR007730.
  
     0.474
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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