| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49394.1 | scsD | HMPREF0621_2030 | HMPREF0621_0643 | Tetratricopeptide repeat protein; Pfam: PF04575; InterPro: IPR007655. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.431 |
| EEX51090.1 | scsD | HMPREF0621_0280 | HMPREF0621_0643 | Hypothetical protein; COG: COG2979; Pfam: PF04391; InterPro: IPR007486. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.475 |
| FabR | oxyR | HMPREF0621_0642 | HMPREF0621_0641 | Transcriptional regulator, TetR family; COG: COG1309; Pfam: PF00440; InterPro: IPR001647. | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.796 |
| FabR | scsD | HMPREF0621_0642 | HMPREF0621_0643 | Transcriptional regulator, TetR family; COG: COG1309; Pfam: PF00440; InterPro: IPR001647. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.773 |
| FabR | slyX | HMPREF0621_0642 | HMPREF0621_0640 | Transcriptional regulator, TetR family; COG: COG1309; Pfam: PF00440; InterPro: IPR001647. | SlyX family protein; COG: COG2900; Pfam: PF04102; InterPro: IPR007236; Belongs to the SlyX family. | 0.689 |
| arcB | fusA | HMPREF0621_1142 | HMPREF0621_0632 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.516 |
| arcB | gap | HMPREF0621_1142 | HMPREF0621_0394 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.596 |
| arcB | putA | HMPREF0621_1142 | HMPREF0621_1408 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.402 |
| arcB | scsD | HMPREF0621_1142 | HMPREF0621_0643 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.433 |
| arcB | trxB | HMPREF0621_1142 | HMPREF0621_1689 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Thioredoxin-disulfide reductase; COG: COG0492; Pfam: PF07992,PF00070; InterPro: IPR005982. | 0.565 |
| fusA | arcB | HMPREF0621_0632 | HMPREF0621_1142 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.516 |
| fusA | gap | HMPREF0621_0632 | HMPREF0621_0394 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.539 |
| fusA | scsD | HMPREF0621_0632 | HMPREF0621_0643 | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.552 |
| gap | arcB | HMPREF0621_0394 | HMPREF0621_1142 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.596 |
| gap | fusA | HMPREF0621_0394 | HMPREF0621_0632 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.539 |
| gap | scsD | HMPREF0621_0394 | HMPREF0621_0643 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057; Pfam: PF00044,PF02800; InterPro: IPR000173; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.425 |
| oxyR | FabR | HMPREF0621_0641 | HMPREF0621_0642 | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | Transcriptional regulator, TetR family; COG: COG1309; Pfam: PF00440; InterPro: IPR001647. | 0.796 |
| oxyR | scsD | HMPREF0621_0641 | HMPREF0621_0643 | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.762 |
| oxyR | slyX | HMPREF0621_0641 | HMPREF0621_0640 | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | SlyX family protein; COG: COG2900; Pfam: PF04102; InterPro: IPR007236; Belongs to the SlyX family. | 0.445 |
| putA | arcB | HMPREF0621_1408 | HMPREF0621_1142 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.402 |