| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MglA_2 | aldA | HMPREF0621_0651 | HMPREF0621_0648 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | 0.455 |
| MglA_2 | fucA | HMPREF0621_0651 | HMPREF0621_0652 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.742 |
| MglA_2 | fucK | HMPREF0621_0651 | HMPREF0621_0654 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. | 0.519 |
| MglA_2 | fucU | HMPREF0621_0651 | HMPREF0621_0653 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | RbsD/FucU transport family protein; Involved in the anomeric conversion of L-fucose. | 0.663 |
| MglA_2 | rbsB2 | HMPREF0621_0651 | HMPREF0621_0649 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | Sugar-binding domain protein; COG: COG1879; Pfam: PF00532. | 0.899 |
| MglA_2 | rbsC2 | HMPREF0621_0651 | HMPREF0621_0650 | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | Branched-chain amino acid ABC transporter, permease protein; COG: COG1172; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.993 |
| aldA | MglA_2 | HMPREF0621_0648 | HMPREF0621_0651 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | 0.455 |
| aldA | fucA | HMPREF0621_0648 | HMPREF0621_0652 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.719 |
| aldA | rbsB2 | HMPREF0621_0648 | HMPREF0621_0649 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Sugar-binding domain protein; COG: COG1879; Pfam: PF00532. | 0.460 |
| aldA | rbsC2 | HMPREF0621_0648 | HMPREF0621_0650 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | Branched-chain amino acid ABC transporter, permease protein; COG: COG1172; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.459 |
| fba | fbaA | HMPREF0621_1958 | HMPREF0621_1859 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.917 |
| fba | fucA | HMPREF0621_1958 | HMPREF0621_0652 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.905 |
| fba | tpiA | HMPREF0621_1958 | HMPREF0621_0703 | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.971 |
| fbaA | fba | HMPREF0621_1859 | HMPREF0621_1958 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | 0.917 |
| fbaA | fucA | HMPREF0621_1859 | HMPREF0621_0652 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | 0.905 |
| fbaA | tpiA | HMPREF0621_1859 | HMPREF0621_0703 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.965 |
| fucA | MglA_2 | HMPREF0621_0652 | HMPREF0621_0651 | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | 0.742 |
| fucA | aldA | HMPREF0621_0652 | HMPREF0621_0648 | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. | 0.719 |
| fucA | fba | HMPREF0621_0652 | HMPREF0621_1958 | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Ketose-bisphosphate aldolase; COG: COG0191; Pfam: PF01116; InterPro: IPR013785. | 0.905 |
| fucA | fbaA | HMPREF0621_0652 | HMPREF0621_1859 | L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.905 |