| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX50688.1 | dlgD | HMPREF0621_0752 | HMPREF0621_0745 | Hypothetical protein. | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | 0.571 |
| EEX50688.1 | gnl | HMPREF0621_0752 | HMPREF0621_0753 | Hypothetical protein. | SMP-30/Gluconolaconase/LRE-like region; COG: COG3386; Pfam: PF08450; InterPro: IPR011042. | 0.806 |
| EEX50688.1 | lyx | HMPREF0621_0752 | HMPREF0621_0754 | Hypothetical protein. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.633 |
| EEX50688.1 | rbsA2 | HMPREF0621_0752 | HMPREF0621_0750 | Hypothetical protein. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | 0.669 |
| EEX50688.1 | rbsC4 | HMPREF0621_0752 | HMPREF0621_0751 | Hypothetical protein. | Branched-chain amino acid ABC transporter, permease protein; COG: COG1172; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.930 |
| FruB | aad | HMPREF0621_1914 | HMPREF0621_0890 | Hypothetical protein; 2.7.1.-. | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.447 |
| FruB | lyx | HMPREF0621_1914 | HMPREF0621_0754 | Hypothetical protein; 2.7.1.-. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.449 |
| UlaG | lyx | HMPREF0621_0236 | HMPREF0621_0754 | Hypothetical protein; COG: COG2220. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.914 |
| UlaG | pyrF | HMPREF0621_0236 | HMPREF0621_0239 | Hypothetical protein; COG: COG2220. | Orotidine 5'-phosphate decarboxylase/HUMPS family; COG: COG0269; Pfam: PF00215; InterPro: IPR013785. | 0.985 |
| UlaG | sgbU | HMPREF0621_0236 | HMPREF0621_2049 | Hypothetical protein; COG: COG2220. | Putative hexulose-6-phosphate isomerase; COG: COG3623; Pfam: PF01261; InterPro: IPR004560. | 0.799 |
| aad | FruB | HMPREF0621_0890 | HMPREF0621_1914 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Hypothetical protein; 2.7.1.-. | 0.447 |
| aad | lyx | HMPREF0621_0890 | HMPREF0621_0754 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.402 |
| dlgD | EEX50688.1 | HMPREF0621_0745 | HMPREF0621_0752 | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | Hypothetical protein. | 0.571 |
| dlgD | gnl | HMPREF0621_0745 | HMPREF0621_0753 | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | SMP-30/Gluconolaconase/LRE-like region; COG: COG3386; Pfam: PF08450; InterPro: IPR011042. | 0.606 |
| dlgD | lyx | HMPREF0621_0745 | HMPREF0621_0754 | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.952 |
| dlgD | rbsA2 | HMPREF0621_0745 | HMPREF0621_0750 | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003439. | 0.519 |
| dlgD | rbsC4 | HMPREF0621_0745 | HMPREF0621_0751 | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | Branched-chain amino acid ABC transporter, permease protein; COG: COG1172; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.536 |
| gnl | EEX50688.1 | HMPREF0621_0753 | HMPREF0621_0752 | SMP-30/Gluconolaconase/LRE-like region; COG: COG3386; Pfam: PF08450; InterPro: IPR011042. | Hypothetical protein. | 0.806 |
| gnl | dlgD | HMPREF0621_0753 | HMPREF0621_0745 | SMP-30/Gluconolaconase/LRE-like region; COG: COG3386; Pfam: PF08450; InterPro: IPR011042. | malate/L-lactate dehydrogenase; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate. | 0.606 |
| gnl | lyx | HMPREF0621_0753 | HMPREF0621_0754 | SMP-30/Gluconolaconase/LRE-like region; COG: COG3386; Pfam: PF08450; InterPro: IPR011042. | Carbohydrate kinase, FGGY family protein; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR000577; Belongs to the FGGY kinase family. | 0.815 |