| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HcpD_2 | LppB_2 | HMPREF0621_0794 | HMPREF0621_0791 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | Hypothetical protein. | 0.435 |
| HcpD_2 | ftsB | HMPREF0621_0794 | HMPREF0621_0798 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.776 |
| HcpD_2 | ispD | HMPREF0621_0794 | HMPREF0621_0797 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.773 |
| HcpD_2 | ispF | HMPREF0621_0794 | HMPREF0621_0796 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.773 |
| HcpD_2 | lppB | HMPREF0621_0794 | HMPREF0621_0792 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | SNARE-like domain protein; COG: COG1238; Pfam: PF09335. | 0.446 |
| HcpD_2 | surE | HMPREF0621_0794 | HMPREF0621_0793 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.550 |
| HcpD_2 | truD | HMPREF0621_0794 | HMPREF0621_0795 | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.773 |
| LppB_1 | LppB_2 | HMPREF0621_0790 | HMPREF0621_0791 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | Hypothetical protein. | 0.671 |
| LppB_1 | ftsB | HMPREF0621_0790 | HMPREF0621_0798 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.522 |
| LppB_1 | ispD | HMPREF0621_0790 | HMPREF0621_0797 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.443 |
| LppB_1 | ispF | HMPREF0621_0790 | HMPREF0621_0796 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.443 |
| LppB_1 | lppB | HMPREF0621_0790 | HMPREF0621_0792 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | SNARE-like domain protein; COG: COG1238; Pfam: PF09335. | 0.684 |
| LppB_1 | surE | HMPREF0621_0790 | HMPREF0621_0793 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.586 |
| LppB_1 | truD | HMPREF0621_0790 | HMPREF0621_0795 | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.443 |
| LppB_2 | HcpD_2 | HMPREF0621_0791 | HMPREF0621_0794 | Hypothetical protein. | Sel1 repeat protein; COG: COG0790; Pfam: PF08238; InterPro: IPR011990. | 0.435 |
| LppB_2 | LppB_1 | HMPREF0621_0791 | HMPREF0621_0790 | Hypothetical protein. | Peptidase, M23 family; COG: COG0739; Pfam: PF01476,PF01551; InterPro: IPR002886. | 0.671 |
| LppB_2 | ftsB | HMPREF0621_0791 | HMPREF0621_0798 | Hypothetical protein. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.435 |
| LppB_2 | ispD | HMPREF0621_0791 | HMPREF0621_0797 | Hypothetical protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.435 |
| LppB_2 | ispF | HMPREF0621_0791 | HMPREF0621_0796 | Hypothetical protein. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.435 |
| LppB_2 | lppB | HMPREF0621_0791 | HMPREF0621_0792 | Hypothetical protein. | SNARE-like domain protein; COG: COG1238; Pfam: PF09335. | 0.753 |