STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. (415 aa)    
Predicted Functional Partners:
acnB
Aconitate hydratase 2; COG: COG1049; Pfam: PF06434,PF00330; InterPro: IPR004406; Belongs to the aconitase/IPM isomerase family.
  
 
 0.974
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00676,PF02779; InterPro: IPR011603.
   
 
 0.971
gltA
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family.
 
 
 0.936
gdhA
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.915
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.883
aspC
Aminotransferase, class I/II; COG: COG1448; Pfam: PF00155; InterPro: IPR000796.
   
 0.877
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.864
aspC2
Aminotransferase AlaT; COG: COG0436; Pfam: PF00155; InterPro: IPR004839.
   
 0.859
aspA
Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708.
     
 0.826
argH
Argininosuccinate lyase; COG: COG0165; Pfam: PF00206; InterPro: IPR009049.
     
 0.825
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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