| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX50576.1 | icd | HMPREF0621_0802 | HMPREF0621_0799 | Hypothetical protein. | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | 0.525 |
| EEX50576.1 | mutT | HMPREF0621_0802 | HMPREF0621_0801 | Hypothetical protein. | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.705 |
| EEX50576.1 | rluE | HMPREF0621_0802 | HMPREF0621_0800 | Hypothetical protein. | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.712 |
| NadR | mutT | HMPREF0621_1980 | HMPREF0621_0801 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.434 |
| dsbA | mutT | HMPREF0621_1910 | HMPREF0621_0801 | Thiol:disulfide interchange protein DsbA; COG: COG0526; Pfam: PF01323; InterPro: IPR012335. | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.422 |
| ftsB | icd | HMPREF0621_0798 | HMPREF0621_0799 | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | 0.468 |
| ftsB | mutT | HMPREF0621_0798 | HMPREF0621_0801 | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.441 |
| icd | EEX50576.1 | HMPREF0621_0799 | HMPREF0621_0802 | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | Hypothetical protein. | 0.525 |
| icd | ftsB | HMPREF0621_0799 | HMPREF0621_0798 | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.468 |
| icd | mutT | HMPREF0621_0799 | HMPREF0621_0801 | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.541 |
| icd | rluE | HMPREF0621_0799 | HMPREF0621_0800 | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.547 |
| mutT | EEX50576.1 | HMPREF0621_0801 | HMPREF0621_0802 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Hypothetical protein. | 0.705 |
| mutT | NadR | HMPREF0621_0801 | HMPREF0621_1980 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 0.434 |
| mutT | dsbA | HMPREF0621_0801 | HMPREF0621_1910 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Thiol:disulfide interchange protein DsbA; COG: COG0526; Pfam: PF01323; InterPro: IPR012335. | 0.422 |
| mutT | ftsB | HMPREF0621_0801 | HMPREF0621_0798 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.441 |
| mutT | icd | HMPREF0621_0801 | HMPREF0621_0799 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | 0.541 |
| mutT | rluE | HMPREF0621_0801 | HMPREF0621_0800 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.795 |
| mutT | yfhD | HMPREF0621_0801 | HMPREF0621_1135 | Hydrolase, NUDIX family; COG: COG0494; Pfam: PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudJ subfamily. | Transglycosylase SLT domain protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. | 0.548 |
| rluE | EEX50576.1 | HMPREF0621_0800 | HMPREF0621_0802 | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | Hypothetical protein. | 0.712 |
| rluE | icd | HMPREF0621_0800 | HMPREF0621_0799 | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | Isocitrate dehydrogenase, NADP-dependent; COG: COG0538; Pfam: PF00180; InterPro: IPR004439. | 0.547 |