STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (538 aa)    
Predicted Functional Partners:
oadA
Oxaloacetate decarboxylase alpha subunit; COG: COG5016; Pfam: PF00682,PF02436,PF00364; InterPro: IPR005776.
    
 0.942
gltA
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family.
  
 
 0.930
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 
 0.929
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.929
pyk
Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.
     
 0.927
ppc
Phosphoenolpyruvate carboxykinase (GTP); Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.927
aad
Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.921
oadB
Sodium ion-translocating decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.
    
 0.913
oadG
Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
    
  0.904
aspA
Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708.
   
 
 0.898
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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