| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX50620.1 | gnd | HMPREF0621_0846 | HMPREF0621_0847 | Hypothetical protein. | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.526 |
| EEX50620.1 | pgl | HMPREF0621_0846 | HMPREF0621_0845 | Hypothetical protein. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.440 |
| aroK-2 | gnd | HMPREF0621_1683 | HMPREF0621_0847 | Shikimate kinase; COG: COG3265; Pfam: PF01202; InterPro: IPR006001. | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.993 |
| aroK-2 | pgl | HMPREF0621_1683 | HMPREF0621_0845 | Shikimate kinase; COG: COG3265; Pfam: PF01202; InterPro: IPR006001. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.932 |
| aroK-2 | rpiA | HMPREF0621_1683 | HMPREF0621_0580 | Shikimate kinase; COG: COG3265; Pfam: PF01202; InterPro: IPR006001. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.424 |
| aroK-2 | zwf | HMPREF0621_1683 | HMPREF0621_0844 | Shikimate kinase; COG: COG3265; Pfam: PF01202; InterPro: IPR006001. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.400 |
| eno | gnd | HMPREF0621_0036 | HMPREF0621_0847 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.498 |
| eno | pgk | HMPREF0621_0036 | HMPREF0621_1861 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.978 |
| eno | rpe | HMPREF0621_0036 | HMPREF0621_0785 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family. | 0.434 |
| eno | rpiA | HMPREF0621_0036 | HMPREF0621_0580 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.417 |
| eno | tal | HMPREF0621_0036 | HMPREF0621_0803 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.895 |
| eno | tkt | HMPREF0621_0036 | HMPREF0621_0756 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.926 |
| eno | zwf | HMPREF0621_0036 | HMPREF0621_0844 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.855 |
| gnd | EEX50620.1 | HMPREF0621_0847 | HMPREF0621_0846 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Hypothetical protein. | 0.526 |
| gnd | aroK-2 | HMPREF0621_0847 | HMPREF0621_1683 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Shikimate kinase; COG: COG3265; Pfam: PF01202; InterPro: IPR006001. | 0.993 |
| gnd | eno | HMPREF0621_0847 | HMPREF0621_0036 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.498 |
| gnd | pgk | HMPREF0621_0847 | HMPREF0621_1861 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Phosphoglycerate kinase; COG: COG0126; Pfam: PF00162; InterPro: IPR001576; Belongs to the phosphoglycerate kinase family. | 0.561 |
| gnd | pgl | HMPREF0621_0847 | HMPREF0621_0845 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.969 |
| gnd | rpe | HMPREF0621_0847 | HMPREF0621_0785 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family. | 0.947 |
| gnd | rpiA | HMPREF0621_0847 | HMPREF0621_0580 | Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.932 |