| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX50656.1 | pabB | HMPREF0621_0882 | HMPREF0621_0883 | Hypothetical protein; InterPro: IPR001544. | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | 0.995 |
| EEX50656.1 | pheA | HMPREF0621_0882 | HMPREF0621_1799 | Hypothetical protein; InterPro: IPR001544. | Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086. | 0.439 |
| EEX50656.1 | trpG2 | HMPREF0621_0882 | HMPREF0621_0884 | Hypothetical protein; InterPro: IPR001544. | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.964 |
| aroC | pabB | HMPREF0621_0980 | HMPREF0621_0883 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | 0.891 |
| aroC | pheA | HMPREF0621_0980 | HMPREF0621_1799 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086. | 0.976 |
| aroC | trpA | HMPREF0621_0980 | HMPREF0621_1420 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.710 |
| aroC | trpC | HMPREF0621_0980 | HMPREF0621_1417 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Indole-3-glycerol phosphate synthase; COG: COG0134; Pfam: PF00218,PF00697; InterPro: IPR013785; Belongs to the TrpC family. | 0.634 |
| aroC | trpD | HMPREF0621_0980 | HMPREF0621_1416 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.515 |
| aroC | trpE | HMPREF0621_0980 | HMPREF0621_1414 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase component I; COG: COG0147; Pfam: PF04715,PF00425; InterPro: IPR005801. | 0.950 |
| aroC | trpG | HMPREF0621_0980 | HMPREF0621_1415 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.956 |
| aroC | trpG2 | HMPREF0621_0980 | HMPREF0621_0884 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.903 |
| aroC | tyrA | HMPREF0621_0980 | HMPREF0621_1324 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; COG: COG0287; Pfam: PF01817,PF02153; InterPro: IPR003099. | 0.995 |
| pabB | EEX50656.1 | HMPREF0621_0883 | HMPREF0621_0882 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Hypothetical protein; InterPro: IPR001544. | 0.995 |
| pabB | aroC | HMPREF0621_0883 | HMPREF0621_0980 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.891 |
| pabB | pheA | HMPREF0621_0883 | HMPREF0621_1799 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086. | 0.901 |
| pabB | trpA | HMPREF0621_0883 | HMPREF0621_1420 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.821 |
| pabB | trpC | HMPREF0621_0883 | HMPREF0621_1417 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Indole-3-glycerol phosphate synthase; COG: COG0134; Pfam: PF00218,PF00697; InterPro: IPR013785; Belongs to the TrpC family. | 0.989 |
| pabB | trpD | HMPREF0621_0883 | HMPREF0621_1416 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.958 |
| pabB | trpE | HMPREF0621_0883 | HMPREF0621_1414 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Anthranilate synthase component I; COG: COG0147; Pfam: PF04715,PF00425; InterPro: IPR005801. | 0.856 |
| pabB | trpG | HMPREF0621_0883 | HMPREF0621_1415 | Chorismate binding enzyme; COG: COG0147; Pfam: PF00425; InterPro: IPR005801. | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.997 |