| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49673.1 | YhcB | HMPREF0621_1720 | HMPREF0621_1632 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | 0.689 |
| EEX49673.1 | YihD | HMPREF0621_1720 | HMPREF0621_1911 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Hypothetical protein; COG: COG3084; Pfam: PF06288; InterPro: IPR009383. | 0.653 |
| EEX49673.1 | YiiS | HMPREF0621_1720 | HMPREF0621_0281 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Hypothetical protein; COG: COG3691; Pfam: PF04175; InterPro: IPR005272. | 0.726 |
| EEX49673.1 | ftsL | HMPREF0621_1720 | HMPREF0621_0342 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.693 |
| EEX49673.1 | kicA | HMPREF0621_1720 | HMPREF0621_1351 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | MukE-like family protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.703 |
| EEX49673.1 | kicB | HMPREF0621_1720 | HMPREF0621_1350 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | KicB killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.694 |
| EEX49673.1 | lapA | HMPREF0621_1720 | HMPREF0621_0994 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.740 |
| EEX49673.1 | mukB | HMPREF0621_1720 | HMPREF0621_1352 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | MukB N-terminal domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. | 0.674 |
| EEX49673.1 | uspA2 | HMPREF0621_1720 | HMPREF0621_0721 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Universal stress family protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.463 |
| EEX49673.1 | zapB | HMPREF0621_1720 | HMPREF0621_0912 | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.710 |
| YhcB | EEX49673.1 | HMPREF0621_1632 | HMPREF0621_1720 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Hypothetical protein; COG: COG2926; Pfam: PF04363; InterPro: IPR007458; Belongs to the UPF0265 family. | 0.689 |
| YhcB | YihD | HMPREF0621_1632 | HMPREF0621_1911 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Hypothetical protein; COG: COG3084; Pfam: PF06288; InterPro: IPR009383. | 0.488 |
| YhcB | YiiS | HMPREF0621_1632 | HMPREF0621_0281 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Hypothetical protein; COG: COG3691; Pfam: PF04175; InterPro: IPR005272. | 0.673 |
| YhcB | ftsL | HMPREF0621_1632 | HMPREF0621_0342 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.701 |
| YhcB | kicA | HMPREF0621_1632 | HMPREF0621_1351 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | MukE-like family protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.715 |
| YhcB | kicB | HMPREF0621_1632 | HMPREF0621_1350 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | KicB killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.746 |
| YhcB | lapA | HMPREF0621_1632 | HMPREF0621_0994 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.742 |
| YhcB | mukB | HMPREF0621_1632 | HMPREF0621_1352 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | MukB N-terminal domain protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. | 0.705 |
| YhcB | uspA2 | HMPREF0621_1632 | HMPREF0621_0721 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Universal stress family protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.722 |
| YhcB | zapB | HMPREF0621_1632 | HMPREF0621_0912 | Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386; 1.10.3.-. | Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.745 |