| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49801.1 | hemG | HMPREF0621_1848 | HMPREF0621_0932 | Hypothetical protein; COG: COG3721; Pfam: PF06228; InterPro: IPR010413. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.417 |
| YigZ | hemG | HMPREF0621_0930 | HMPREF0621_0932 | YigZ family protein; COG: COG1739; Pfam: PF01205,PF09186; InterPro: IPR015796. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.621 |
| YigZ | trkH | HMPREF0621_0930 | HMPREF0621_0931 | YigZ family protein; COG: COG1739; Pfam: PF01205,PF09186; InterPro: IPR015796. | Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.621 |
| YigZ | tusA | HMPREF0621_0930 | HMPREF0621_0929 | YigZ family protein; COG: COG1739; Pfam: PF01205,PF09186; InterPro: IPR015796. | Putative sulfur transfer protein SirA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.592 |
| cyaA | ftsL | HMPREF0621_1900 | HMPREF0621_0342 | Adenylate cyclase, class I; COG: COG3072; Pfam: PF01295; InterPro: IPR000274; Belongs to the adenylyl cyclase class-1 family. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.588 |
| cyaA | hemG | HMPREF0621_1900 | HMPREF0621_0932 | Adenylate cyclase, class I; COG: COG3072; Pfam: PF01295; InterPro: IPR000274; Belongs to the adenylyl cyclase class-1 family. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.520 |
| ftsL | cyaA | HMPREF0621_0342 | HMPREF0621_1900 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Adenylate cyclase, class I; COG: COG3072; Pfam: PF01295; InterPro: IPR000274; Belongs to the adenylyl cyclase class-1 family. | 0.588 |
| ftsL | hemG | HMPREF0621_0342 | HMPREF0621_0932 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.415 |
| hemG | EEX49801.1 | HMPREF0621_0932 | HMPREF0621_1848 | Putative protoporphyrinogen oxidase; COG: COG4635. | Hypothetical protein; COG: COG3721; Pfam: PF06228; InterPro: IPR010413. | 0.417 |
| hemG | YigZ | HMPREF0621_0932 | HMPREF0621_0930 | Putative protoporphyrinogen oxidase; COG: COG4635. | YigZ family protein; COG: COG1739; Pfam: PF01205,PF09186; InterPro: IPR015796. | 0.621 |
| hemG | cyaA | HMPREF0621_0932 | HMPREF0621_1900 | Putative protoporphyrinogen oxidase; COG: COG4635. | Adenylate cyclase, class I; COG: COG3072; Pfam: PF01295; InterPro: IPR000274; Belongs to the adenylyl cyclase class-1 family. | 0.520 |
| hemG | ftsL | HMPREF0621_0932 | HMPREF0621_0342 | Putative protoporphyrinogen oxidase; COG: COG4635. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.415 |
| hemG | hemH | HMPREF0621_0932 | HMPREF0621_1680 | Putative protoporphyrinogen oxidase; COG: COG4635. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.924 |
| hemG | hemN | HMPREF0621_0932 | HMPREF0621_1888 | Putative protoporphyrinogen oxidase; COG: COG4635. | Coproporphyrinogen dehydrogenase; COG: COG0635; Pfam: PF04055,PF06969; InterPro: IPR004558; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.912 |
| hemG | trkH | HMPREF0621_0932 | HMPREF0621_0931 | Putative protoporphyrinogen oxidase; COG: COG4635. | Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. | 0.794 |
| hemG | tusA | HMPREF0621_0932 | HMPREF0621_0929 | Putative protoporphyrinogen oxidase; COG: COG4635. | Putative sulfur transfer protein SirA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.465 |
| hemH | hemG | HMPREF0621_1680 | HMPREF0621_0932 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.924 |
| hemH | hemN | HMPREF0621_1680 | HMPREF0621_1888 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Coproporphyrinogen dehydrogenase; COG: COG0635; Pfam: PF04055,PF06969; InterPro: IPR004558; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.509 |
| hemN | hemG | HMPREF0621_1888 | HMPREF0621_0932 | Coproporphyrinogen dehydrogenase; COG: COG0635; Pfam: PF04055,PF06969; InterPro: IPR004558; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Putative protoporphyrinogen oxidase; COG: COG4635. | 0.912 |
| hemN | hemH | HMPREF0621_1888 | HMPREF0621_1680 | Coproporphyrinogen dehydrogenase; COG: COG0635; Pfam: PF04055,PF06969; InterPro: IPR004558; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.509 |