| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mlc | nagE | HMPREF0621_1388 | HMPREF0621_0953 | Hypothetical protein. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.759 |
| murQ | nagA | HMPREF0621_2011 | HMPREF0621_0951 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.982 |
| murQ | nagE | HMPREF0621_2011 | HMPREF0621_0953 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.942 |
| murQ | nagK | HMPREF0621_2011 | HMPREF0621_1596 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.900 |
| murQ | nanE | HMPREF0621_2011 | HMPREF0621_0016 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.906 |
| murQ | ptbA | HMPREF0621_2011 | HMPREF0621_1176 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.911 |
| nagA | murQ | HMPREF0621_0951 | HMPREF0621_2011 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.982 |
| nagA | nagE | HMPREF0621_0951 | HMPREF0621_0953 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.967 |
| nagA | nagK | HMPREF0621_0951 | HMPREF0621_1596 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.905 |
| nagA | nanE | HMPREF0621_0951 | HMPREF0621_0016 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.944 |
| nagA | ptbA | HMPREF0621_0951 | HMPREF0621_1176 | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.434 |
| nagC | nagE | HMPREF0621_1627 | HMPREF0621_0953 | ROK family protein; COG: COG1940; Pfam: PF01047,PF00480; InterPro: IPR000600. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.759 |
| nagC2 | nagE | HMPREF0621_1960 | HMPREF0621_0953 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.759 |
| nagE | Mlc | HMPREF0621_0953 | HMPREF0621_1388 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | Hypothetical protein. | 0.759 |
| nagE | murQ | HMPREF0621_0953 | HMPREF0621_2011 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.942 |
| nagE | nagA | HMPREF0621_0953 | HMPREF0621_0951 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.967 |
| nagE | nagC | HMPREF0621_0953 | HMPREF0621_1627 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | ROK family protein; COG: COG1940; Pfam: PF01047,PF00480; InterPro: IPR000600. | 0.759 |
| nagE | nagC2 | HMPREF0621_0953 | HMPREF0621_1960 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.759 |
| nagE | nagK | HMPREF0621_0953 | HMPREF0621_1596 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | ROK family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.974 |
| nagE | nanE | HMPREF0621_0953 | HMPREF0621_0016 | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.946 |