STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YbfFHydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. (285 aa)    
Predicted Functional Partners:
menE
O-succinylbenzoate-CoA ligase; COG: COG0318; Pfam: PF00501; InterPro: IPR010192.
   
 
 0.658
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.651
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.642
seqA
SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
       0.611
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.605
kefA
Transporter, small conductance mechanosensitive ion channel MscS family protein; COG: COG3264; Pfam: PF00924; InterPro: IPR006685.
       0.579
fldA
Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
     
 0.555
ybfE
LexA regulated protein.
       0.549
trpC
Indole-3-glycerol phosphate synthase; COG: COG0134; Pfam: PF00218,PF00697; InterPro: IPR013785; Belongs to the TrpC family.
   
 
 0.536
fur
Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family.
       0.506
Your Current Organism:
Pasteurella dagmatis
NCBI taxonomy Id: 667128
Other names: P. dagmatis ATCC 43325, Pasteurella dagmatis ATCC 43325, Pasteurella dagmatis str. ATCC 43325, Pasteurella dagmatis strain ATCC 43325
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