| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NadR | fur | HMPREF0621_1980 | HMPREF0621_0987 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.572 |
| NadR | polA | HMPREF0621_1980 | HMPREF0621_0286 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.518 |
| YbfF | fldA | HMPREF0621_0984 | HMPREF0621_0986 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.555 |
| YbfF | fur | HMPREF0621_0984 | HMPREF0621_0987 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.506 |
| YbfF | ybfE | HMPREF0621_0984 | HMPREF0621_0985 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | LexA regulated protein. | 0.549 |
| ahpC | fur | HMPREF0621_1510 | HMPREF0621_0987 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.720 |
| ahpC | trxA | HMPREF0621_1510 | HMPREF0621_0404 | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.496 |
| fldA | YbfF | HMPREF0621_0986 | HMPREF0621_0984 | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.555 |
| fldA | fur | HMPREF0621_0986 | HMPREF0621_0987 | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | 0.793 |
| fldA | ybfE | HMPREF0621_0986 | HMPREF0621_0985 | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | LexA regulated protein. | 0.808 |
| fur | NadR | HMPREF0621_0987 | HMPREF0621_1980 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 0.572 |
| fur | YbfF | HMPREF0621_0987 | HMPREF0621_0984 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.506 |
| fur | ahpC | HMPREF0621_0987 | HMPREF0621_1510 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Antioxidant, AhpC/TSA family; COG: COG0450; Pfam: PF00578; InterPro: IPR012335. | 0.720 |
| fur | fldA | HMPREF0621_0987 | HMPREF0621_0986 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. | 0.793 |
| fur | polA | HMPREF0621_0987 | HMPREF0621_0286 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.490 |
| fur | rpoA | HMPREF0621_0987 | HMPREF0621_1983 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.603 |
| fur | rpoD | HMPREF0621_0987 | HMPREF0621_0043 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.489 |
| fur | rpoH | HMPREF0621_0987 | HMPREF0621_0808 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.490 |
| fur | trxA | HMPREF0621_0987 | HMPREF0621_0404 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | Thioredoxin; COG: COG0526; Pfam: PF00085; InterPro: IPR012335; Belongs to the thioredoxin family. | 0.510 |
| fur | ybfE | HMPREF0621_0987 | HMPREF0621_0985 | Transcriptional regulator, Fur family; COG: COG0735; Pfam: PF01475; InterPro: IPR002481; Belongs to the Fur family. | LexA regulated protein. | 0.721 |