| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX50450.1 | der | HMPREF0621_1073 | HMPREF0621_1072 | Hypothetical protein. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.661 |
| cmk | der | HMPREF0621_0997 | HMPREF0621_1072 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.971 |
| cmk | gpsA | HMPREF0621_0997 | HMPREF0621_0857 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.425 |
| cmk | pheT | HMPREF0621_0997 | HMPREF0621_1376 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.403 |
| cmk | rluB | HMPREF0621_0997 | HMPREF0621_1326 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.702 |
| cmk | rluE | HMPREF0621_0997 | HMPREF0621_0800 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.496 |
| cmk | rsuA | HMPREF0621_0997 | HMPREF0621_0488 | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.496 |
| der | EEX50450.1 | HMPREF0621_1072 | HMPREF0621_1073 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Hypothetical protein. | 0.661 |
| der | cmk | HMPREF0621_1072 | HMPREF0621_0997 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cytidylate kinase; COG: COG0283; Pfam: PF02224; InterPro: IPR003136. | 0.971 |
| der | dnaG | HMPREF0621_1072 | HMPREF0621_0044 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.890 |
| der | gpsA | HMPREF0621_1072 | HMPREF0621_0857 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.923 |
| der | pheT | HMPREF0621_1072 | HMPREF0621_1376 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.675 |
| der | rluB | HMPREF0621_1072 | HMPREF0621_1326 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.809 |
| der | rluE | HMPREF0621_1072 | HMPREF0621_0800 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pseudouridylate synthase; COG: COG1187; Pfam: PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.708 |
| der | rsuA | HMPREF0621_1072 | HMPREF0621_0488 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Pseudouridylate synthase; COG: COG1187; Pfam: PF01479,PF00849; InterPro: IPR000748; Belongs to the pseudouridine synthase RsuA family. | 0.668 |
| der | secA | HMPREF0621_1072 | HMPREF0621_0062 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.664 |
| der | typA | HMPREF0621_1072 | HMPREF0621_0106 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.701 |
| dnaG | der | HMPREF0621_0044 | HMPREF0621_1072 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.890 |
| dnaG | pheT | HMPREF0621_0044 | HMPREF0621_1376 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | phenylalanine--tRNA ligase, beta subunit; COG: COG0072; Pfam: PF01588,PF03483,PF03484,PF03147; InterPro: IPR004532; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.547 |
| dnaG | secA | HMPREF0621_0044 | HMPREF0621_0062 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.588 |