| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cas3 | cas1 | HMPREF0621_1143 | HMPREF0621_1144 | CRISPR-associated helicase Cas3; InterPro: IPR013395. | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.973 |
| Cas3 | csy1 | HMPREF0621_1143 | HMPREF0621_1151 | CRISPR-associated helicase Cas3; InterPro: IPR013395. | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | 0.884 |
| Cas3 | csy2 | HMPREF0621_1143 | HMPREF0621_1150 | CRISPR-associated helicase Cas3; InterPro: IPR013395. | CRISPR-associated protein, Csy2 family; InterPro: IPR013398. | 0.884 |
| Cas3 | csy3 | HMPREF0621_1143 | HMPREF0621_1149 | CRISPR-associated helicase Cas3; InterPro: IPR013395. | CRISPR-associated protein, Csy3 family; InterPro: IPR013399. | 0.884 |
| Cas3 | csy4 | HMPREF0621_1143 | HMPREF0621_1148 | CRISPR-associated helicase Cas3; InterPro: IPR013395. | CRISPR-derived RNA endonuclease Csy4; InterPro: IPR013396. | 0.885 |
| EEX50244.1 | EEX50294.1 | HMPREF0621_1315 | HMPREF0621_1141 | TIGR01619 family protein; Pfam: PF05117,PF06877; InterPro: IPR006506. | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | 0.754 |
| EEX50244.1 | csy4 | HMPREF0621_1315 | HMPREF0621_1148 | TIGR01619 family protein; Pfam: PF05117,PF06877; InterPro: IPR006506. | CRISPR-derived RNA endonuclease Csy4; InterPro: IPR013396. | 0.428 |
| EEX50244.1 | hasR | HMPREF0621_1315 | HMPREF0621_0782 | TIGR01619 family protein; Pfam: PF05117,PF06877; InterPro: IPR006506. | TonB-dependent heme/hemoglobin receptor family protein; Pfam: PF07715,PF00593; InterPro: IPR000531. | 0.709 |
| EEX50294.1 | EEX50244.1 | HMPREF0621_1141 | HMPREF0621_1315 | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | TIGR01619 family protein; Pfam: PF05117,PF06877; InterPro: IPR006506. | 0.754 |
| EEX50294.1 | csy1 | HMPREF0621_1141 | HMPREF0621_1151 | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | 0.402 |
| EEX50294.1 | csy4 | HMPREF0621_1141 | HMPREF0621_1148 | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | CRISPR-derived RNA endonuclease Csy4; InterPro: IPR013396. | 0.425 |
| EEX50294.1 | hasR | HMPREF0621_1141 | HMPREF0621_0782 | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | TonB-dependent heme/hemoglobin receptor family protein; Pfam: PF07715,PF00593; InterPro: IPR000531. | 0.577 |
| cas1 | Cas3 | HMPREF0621_1144 | HMPREF0621_1143 | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | CRISPR-associated helicase Cas3; InterPro: IPR013395. | 0.973 |
| cas1 | csy1 | HMPREF0621_1144 | HMPREF0621_1151 | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | 0.794 |
| cas1 | csy2 | HMPREF0621_1144 | HMPREF0621_1150 | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | CRISPR-associated protein, Csy2 family; InterPro: IPR013398. | 0.800 |
| cas1 | csy3 | HMPREF0621_1144 | HMPREF0621_1149 | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | CRISPR-associated protein, Csy3 family; InterPro: IPR013399. | 0.800 |
| cas1 | csy4 | HMPREF0621_1144 | HMPREF0621_1148 | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | CRISPR-derived RNA endonuclease Csy4; InterPro: IPR013396. | 0.820 |
| csy1 | Cas3 | HMPREF0621_1151 | HMPREF0621_1143 | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | CRISPR-associated helicase Cas3; InterPro: IPR013395. | 0.884 |
| csy1 | EEX50294.1 | HMPREF0621_1151 | HMPREF0621_1141 | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | Hypothetical protein; COG: COG3774; Pfam: PF04488; InterPro: IPR007577. | 0.402 |
| csy1 | cas1 | HMPREF0621_1151 | HMPREF0621_1144 | CRISPR-associated protein, Csy1 family; InterPro: IPR013397. | CRISPR-associated endonuclease Cas1, YPEST subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.794 |