| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FruB | manX | HMPREF0621_1914 | HMPREF0621_1718 | Hypothetical protein; 2.7.1.-. | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | 0.999 |
| FruB | murP | HMPREF0621_1914 | HMPREF0621_2012 | Hypothetical protein; 2.7.1.-. | N-acetylmuramic acid phosphotransfer permease; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR003352. | 0.651 |
| FruB | nagE | HMPREF0621_1914 | HMPREF0621_0953 | Hypothetical protein; 2.7.1.-. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.651 |
| FruB | pfkB | HMPREF0621_1914 | HMPREF0621_1915 | Hypothetical protein; 2.7.1.-. | 1-phosphofructokinase; COG: COG1105; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family. | 0.989 |
| FruB | ptbA | HMPREF0621_1914 | HMPREF0621_1176 | Hypothetical protein; 2.7.1.-. | PTS system, glucose subfamily, IIA component; COG: COG2190; Pfam: PF00358; InterPro: IPR001127. | 0.702 |
| FruB | ptsG | HMPREF0621_1914 | HMPREF0621_0763 | Hypothetical protein; 2.7.1.-. | PTS system, glucose-like IIB component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR003352. | 0.651 |
| FruB | ptsN | HMPREF0621_1914 | HMPREF0621_1774 | Hypothetical protein; 2.7.1.-. | PTS IIA-like nitrogen-regulatory protein PtsN; COG: COG1762; Pfam: PF00359; InterPro: IPR002178. | 0.574 |
| FruB | ptsP | HMPREF0621_1914 | HMPREF0621_1175 | Hypothetical protein; 2.7.1.-. | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.889 |
| FruB | treP | HMPREF0621_1914 | HMPREF0621_0485 | Hypothetical protein; 2.7.1.-. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.651 |
| manX | FruB | HMPREF0621_1718 | HMPREF0621_1914 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | Hypothetical protein; 2.7.1.-. | 0.999 |
| manX | murP | HMPREF0621_1718 | HMPREF0621_2012 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | N-acetylmuramic acid phosphotransfer permease; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR003352. | 0.665 |
| manX | nagE | HMPREF0621_1718 | HMPREF0621_0953 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | PTS system, N-acetylglucosamine-specific IIBC component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR010974. | 0.540 |
| manX | pfkB | HMPREF0621_1718 | HMPREF0621_1915 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | 1-phosphofructokinase; COG: COG1105; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family. | 0.527 |
| manX | ptsG | HMPREF0621_1718 | HMPREF0621_0763 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | PTS system, glucose-like IIB component; COG: COG1263; Pfam: PF02378,PF00367; InterPro: IPR003352. | 0.540 |
| manX | ptsH | HMPREF0621_1718 | HMPREF0621_1174 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | Phosphocarrier, HPr family; COG: COG1925; Pfam: PF00381; InterPro: IPR000032. | 0.999 |
| manX | ptsN | HMPREF0621_1718 | HMPREF0621_1774 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | PTS IIA-like nitrogen-regulatory protein PtsN; COG: COG1762; Pfam: PF00359; InterPro: IPR002178. | 0.605 |
| manX | ptsP | HMPREF0621_1718 | HMPREF0621_1175 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.626 |
| manX | treP | HMPREF0621_1718 | HMPREF0621_0485 | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | PTS system trehalose-specific IIBC component; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR011296. | 0.611 |
| murP | FruB | HMPREF0621_2012 | HMPREF0621_1914 | N-acetylmuramic acid phosphotransfer permease; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR003352. | Hypothetical protein; 2.7.1.-. | 0.651 |
| murP | manX | HMPREF0621_2012 | HMPREF0621_1718 | N-acetylmuramic acid phosphotransfer permease; COG: COG1263; Pfam: PF00367,PF02378; InterPro: IPR003352. | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | 0.665 |