| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX51393.1 | YfbV | HMPREF0621_0197 | HMPREF0621_1307 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | 0.756 |
| EEX51393.1 | lptC | HMPREF0621_0197 | HMPREF0621_1771 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.768 |
| EEX51393.1 | metJ | HMPREF0621_0197 | HMPREF0621_0716 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.767 |
| EEX51393.1 | rraB | HMPREF0621_0197 | HMPREF0621_2015 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.772 |
| EEX51393.1 | seqA | HMPREF0621_0197 | HMPREF0621_0983 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.764 |
| EEX51393.1 | ttg2D | HMPREF0621_0197 | HMPREF0621_1767 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Toluene tolerance protein Ttg2D; COG: COG2854; Pfam: PF05494; InterPro: IPR008869. | 0.489 |
| EEX51393.1 | yfcN | HMPREF0621_0197 | HMPREF0621_1205 | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.549 |
| YfbV | EEX51393.1 | HMPREF0621_1307 | HMPREF0621_0197 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | 0.756 |
| YfbV | lptC | HMPREF0621_1307 | HMPREF0621_1771 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.762 |
| YfbV | metJ | HMPREF0621_1307 | HMPREF0621_0716 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.759 |
| YfbV | rraB | HMPREF0621_1307 | HMPREF0621_2015 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.769 |
| YfbV | seqA | HMPREF0621_1307 | HMPREF0621_0983 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.771 |
| YfbV | ttg2D | HMPREF0621_1307 | HMPREF0621_1767 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Toluene tolerance protein Ttg2D; COG: COG2854; Pfam: PF05494; InterPro: IPR008869. | 0.459 |
| YfbV | yfcN | HMPREF0621_1307 | HMPREF0621_1205 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Smr domain protein; COG: COG2840; Pfam: PF01713; InterPro: IPR002625; Belongs to the UPF0115 family. | 0.562 |
| lptC | EEX51393.1 | HMPREF0621_1771 | HMPREF0621_0197 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Hypothetical protein; COG: COG2921; Pfam: PF04359; InterPro: IPR007454; Belongs to the UPF0250 family. | 0.768 |
| lptC | YfbV | HMPREF0621_1771 | HMPREF0621_1307 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | 0.762 |
| lptC | lptD | HMPREF0621_1771 | HMPREF0621_0805 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.768 |
| lptC | metJ | HMPREF0621_1771 | HMPREF0621_0716 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.754 |
| lptC | rraB | HMPREF0621_1771 | HMPREF0621_2015 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.771 |
| lptC | seqA | HMPREF0621_1771 | HMPREF0621_0983 | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.773 |