| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CysP | EEX50153.1 | HMPREF0621_1225 | HMPREF0621_1224 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | 0.623 |
| CysP | EEX50155.1 | HMPREF0621_1225 | HMPREF0621_1226 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | TIGR00153 family protein; COG: COG1392; Pfam: PF01865; InterPro: IPR002727. | 0.979 |
| CysP | EEX50156.1 | HMPREF0621_1225 | HMPREF0621_1227 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | Adenylate cyclase; COG: COG3025; Pfam: PF01928; InterPro: IPR008172. | 0.512 |
| CysP | cca | HMPREF0621_1225 | HMPREF0621_1223 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | tRNA nucleotidyltransferase/poly(A) polymerase family protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.593 |
| CysP | ispE | HMPREF0621_1225 | HMPREF0621_1221 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.555 |
| CysP | lolB | HMPREF0621_1225 | HMPREF0621_1222 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.493 |
| CysP | prs | HMPREF0621_1225 | HMPREF0621_1220 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.474 |
| CysP | radA | HMPREF0621_1225 | HMPREF0621_1228 | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.471 |
| EEX49532.1 | EEX50155.1 | HMPREF0621_1887 | HMPREF0621_1226 | Hypothetical protein. | TIGR00153 family protein; COG: COG1392; Pfam: PF01865; InterPro: IPR002727. | 0.468 |
| EEX49532.1 | EEX50156.1 | HMPREF0621_1887 | HMPREF0621_1227 | Hypothetical protein. | Adenylate cyclase; COG: COG3025; Pfam: PF01928; InterPro: IPR008172. | 0.593 |
| EEX49532.1 | pilF | HMPREF0621_1887 | HMPREF0621_0499 | Hypothetical protein. | Type IV pilus biogenesis/stability protein PilW; COG: COG3063; Pfam: PF07719,PF00515; InterPro: IPR013360. | 0.409 |
| EEX50153.1 | CysP | HMPREF0621_1224 | HMPREF0621_1225 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | 0.623 |
| EEX50153.1 | EEX50155.1 | HMPREF0621_1224 | HMPREF0621_1226 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | TIGR00153 family protein; COG: COG1392; Pfam: PF01865; InterPro: IPR002727. | 0.564 |
| EEX50153.1 | EEX50156.1 | HMPREF0621_1224 | HMPREF0621_1227 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | Adenylate cyclase; COG: COG3025; Pfam: PF01928; InterPro: IPR008172. | 0.424 |
| EEX50153.1 | cca | HMPREF0621_1224 | HMPREF0621_1223 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | tRNA nucleotidyltransferase/poly(A) polymerase family protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.809 |
| EEX50153.1 | ispE | HMPREF0621_1224 | HMPREF0621_1221 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.669 |
| EEX50153.1 | lolB | HMPREF0621_1224 | HMPREF0621_1222 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.729 |
| EEX50153.1 | prs | HMPREF0621_1224 | HMPREF0621_1220 | Hypothetical protein; COG: COG3103; InterPro: IPR003646. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.543 |
| EEX50155.1 | CysP | HMPREF0621_1226 | HMPREF0621_1225 | TIGR00153 family protein; COG: COG1392; Pfam: PF01865; InterPro: IPR002727. | Phosphate transporter family protein; COG: COG0306; Pfam: PF01384; InterPro: IPR001204. | 0.979 |
| EEX50155.1 | EEX49532.1 | HMPREF0621_1226 | HMPREF0621_1887 | TIGR00153 family protein; COG: COG1392; Pfam: PF01865; InterPro: IPR002727. | Hypothetical protein. | 0.468 |