| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49730.1 | ycgL | HMPREF0621_1777 | HMPREF0621_1277 | Cupin family protein; COG: COG2850; Pfam: PF08007; InterPro: IPR013109. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.490 |
| EEX51377.1 | YigA | HMPREF0621_0181 | HMPREF0621_0028 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Hypothetical protein; COG: COG3159; Pfam: PF04340; InterPro: IPR007435. | 0.416 |
| EEX51377.1 | hflD | HMPREF0621_0181 | HMPREF0621_1872 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | 0.698 |
| EEX51377.1 | ycgL | HMPREF0621_0181 | HMPREF0621_1277 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.540 |
| EEX51377.1 | yhgI | HMPREF0621_0181 | HMPREF0621_0850 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.446 |
| EEX51377.1 | zipA | HMPREF0621_0181 | HMPREF0621_0033 | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.504 |
| YigA | EEX51377.1 | HMPREF0621_0028 | HMPREF0621_0181 | Hypothetical protein; COG: COG3159; Pfam: PF04340; InterPro: IPR007435. | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | 0.416 |
| YigA | ycgL | HMPREF0621_0028 | HMPREF0621_1277 | Hypothetical protein; COG: COG3159; Pfam: PF04340; InterPro: IPR007435. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.447 |
| hflD | EEX51377.1 | HMPREF0621_1872 | HMPREF0621_0181 | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | Putative ACR, COG1399; COG: COG1399; Pfam: PF02620; InterPro: IPR003772. | 0.698 |
| hflD | rnt | HMPREF0621_1872 | HMPREF0621_0425 | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.651 |
| hflD | ycgL | HMPREF0621_1872 | HMPREF0621_1277 | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.710 |
| hflD | ygdH | HMPREF0621_1872 | HMPREF0621_1483 | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | Putative lysine decarboxylase; COG: COG1611; Pfam: PF03641; InterPro: IPR005269. | 0.525 |
| hflD | zipA | HMPREF0621_1872 | HMPREF0621_0033 | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.590 |
| minC | ycgL | HMPREF0621_1276 | HMPREF0621_1277 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.607 |
| rnd | rnt | HMPREF0621_1304 | HMPREF0621_0425 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.543 |
| rnd | ycgL | HMPREF0621_1304 | HMPREF0621_1277 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.638 |
| rnt | hflD | HMPREF0621_0425 | HMPREF0621_1872 | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | Hypothetical protein; COG: COG2915; Pfam: PF04356; InterPro: IPR007451. | 0.651 |
| rnt | rnd | HMPREF0621_0425 | HMPREF0621_1304 | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.543 |
| rnt | ycgL | HMPREF0621_0425 | HMPREF0621_1277 | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.470 |
| rnt | yhgI | HMPREF0621_0425 | HMPREF0621_0850 | Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.428 |