| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AcyP | ackA | HMPREF0621_1210 | HMPREF0621_1306 | Acylphosphatase; Pfam: PF00708; InterPro: IPR001792. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.909 |
| AcyP | maeB | HMPREF0621_1210 | HMPREF0621_0489 | Acylphosphatase; Pfam: PF00708; InterPro: IPR001792. | Phosphate acetyl/butyryl transferase; COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. | 0.441 |
| AcyP | pta | HMPREF0621_1210 | HMPREF0621_1305 | Acylphosphatase; Pfam: PF00708; InterPro: IPR001792. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.911 |
| EEX49631.1 | YkgG | HMPREF0621_1678 | HMPREF0621_1867 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Hypothetical protein; COG: COG1556; Pfam: PF02589; InterPro: IPR003741. | 0.765 |
| EEX49631.1 | aad | HMPREF0621_1678 | HMPREF0621_0890 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.664 |
| EEX49631.1 | ackA | HMPREF0621_1678 | HMPREF0621_1306 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.440 |
| EEX49631.1 | gltA | HMPREF0621_1678 | HMPREF0621_1508 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | 0.512 |
| EEX49631.1 | maeB | HMPREF0621_1678 | HMPREF0621_0489 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Phosphate acetyl/butyryl transferase; COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. | 0.670 |
| EEX49631.1 | pta | HMPREF0621_1678 | HMPREF0621_1305 | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.599 |
| YfbV | ackA | HMPREF0621_1307 | HMPREF0621_1306 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.522 |
| YfbV | pta | HMPREF0621_1307 | HMPREF0621_1305 | Hypothetical protein; COG: COG3092; Pfam: PF04217; InterPro: IPR007334. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.461 |
| YkgG | EEX49631.1 | HMPREF0621_1867 | HMPREF0621_1678 | Hypothetical protein; COG: COG1556; Pfam: PF02589; InterPro: IPR003741. | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | 0.765 |
| YkgG | ackA | HMPREF0621_1867 | HMPREF0621_1306 | Hypothetical protein; COG: COG1556; Pfam: PF02589; InterPro: IPR003741. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.523 |
| YkgG | pta | HMPREF0621_1867 | HMPREF0621_1305 | Hypothetical protein; COG: COG1556; Pfam: PF02589; InterPro: IPR003741. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.750 |
| aad | EEX49631.1 | HMPREF0621_0890 | HMPREF0621_1678 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913,PF00037; InterPro: IPR004113. | 0.664 |
| aad | ackA | HMPREF0621_0890 | HMPREF0621_1306 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.503 |
| aad | gltA | HMPREF0621_0890 | HMPREF0621_1508 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR010953; Belongs to the citrate synthase family. | 0.633 |
| aad | maeB | HMPREF0621_0890 | HMPREF0621_0489 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyl/butyryl transferase; COG: COG0281; Pfam: PF00390,PF03949,PF01515; InterPro: IPR002505. | 0.736 |
| aad | metG | HMPREF0621_0890 | HMPREF0621_1154 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.431 |
| aad | pta | HMPREF0621_0890 | HMPREF0621_1305 | Alcohol dehydrogenase, iron-dependent; COG: COG1454; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.959 |