| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49955.1 | EEX49958.1 | HMPREF0621_1478 | HMPREF0621_1481 | Hypothetical protein; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Hypothetical protein; COG: COG5595. | 0.425 |
| EEX49955.1 | YqcC | HMPREF0621_1478 | HMPREF0621_1480 | Hypothetical protein; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | 0.588 |
| EEX49955.1 | truC | HMPREF0621_1478 | HMPREF0621_1479 | Hypothetical protein; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | RNA pseudouridine synthase; COG: COG0564; Pfam: PF00849; InterPro: IPR006145. | 0.588 |
| EEX49958.1 | EEX49955.1 | HMPREF0621_1481 | HMPREF0621_1478 | Hypothetical protein; COG: COG5595. | Hypothetical protein; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | 0.425 |
| EEX49958.1 | YqcC | HMPREF0621_1481 | HMPREF0621_1480 | Hypothetical protein; COG: COG5595. | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | 0.623 |
| EEX49958.1 | truC | HMPREF0621_1481 | HMPREF0621_1479 | Hypothetical protein; COG: COG5595. | RNA pseudouridine synthase; COG: COG0564; Pfam: PF00849; InterPro: IPR006145. | 0.564 |
| EEX51031.1 | YqcC | HMPREF0621_0618 | HMPREF0621_1480 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | 0.448 |
| EEX51031.1 | ndpA | HMPREF0621_0618 | HMPREF0621_0532 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Nucleoid-associated protein NdpA; COG: COG3081; Pfam: PF04245; InterPro: IPR007358. | 0.545 |
| EEX51031.1 | slmA | HMPREF0621_0618 | HMPREF0621_0122 | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | Transcriptional regulator, TetR family; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.442 |
| YqcC | EEX49955.1 | HMPREF0621_1480 | HMPREF0621_1478 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Hypothetical protein; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | 0.588 |
| YqcC | EEX49958.1 | HMPREF0621_1480 | HMPREF0621_1481 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Hypothetical protein; COG: COG5595. | 0.623 |
| YqcC | EEX51031.1 | HMPREF0621_1480 | HMPREF0621_0618 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Hypothetical protein; COG: COG3068; Pfam: PF04222; InterPro: IPR007338. | 0.448 |
| YqcC | murQ | HMPREF0621_1480 | HMPREF0621_2011 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.499 |
| YqcC | nagZ | HMPREF0621_1480 | HMPREF0621_1109 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.499 |
| YqcC | ndpA | HMPREF0621_1480 | HMPREF0621_0532 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Nucleoid-associated protein NdpA; COG: COG3081; Pfam: PF04245; InterPro: IPR007358. | 0.443 |
| YqcC | slmA | HMPREF0621_1480 | HMPREF0621_0122 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Transcriptional regulator, TetR family; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.494 |
| YqcC | thiI | HMPREF0621_1480 | HMPREF0621_1440 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.489 |
| YqcC | truC | HMPREF0621_1480 | HMPREF0621_1479 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | RNA pseudouridine synthase; COG: COG0564; Pfam: PF00849; InterPro: IPR006145. | 0.850 |
| YqcC | yhgI | HMPREF0621_1480 | HMPREF0621_0850 | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.515 |
| murQ | YqcC | HMPREF0621_2011 | HMPREF0621_1480 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | Hypothetical protein; COG: COG3098; Pfam: PF04287; InterPro: IPR007384. | 0.499 |