| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49603.1 | lpxK | HMPREF0621_1650 | HMPREF0621_1651 | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.794 |
| EEX49603.1 | msbA | HMPREF0621_1650 | HMPREF0621_1652 | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.616 |
| EEX49603.1 | rec | HMPREF0621_1650 | HMPREF0621_1653 | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.694 |
| EEX49603.1 | uvrC | HMPREF0621_1650 | HMPREF0621_1648 | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.609 |
| comF | dprA | HMPREF0621_0849 | HMPREF0621_0823 | comF family protein; COG: COG1040; Pfam: PF00156. | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | 0.908 |
| comF | pilB | HMPREF0621_0849 | HMPREF0621_1094 | comF family protein; COG: COG1040; Pfam: PF00156. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF05157,PF00437; InterPro: IPR001482. | 0.468 |
| comF | pilC | HMPREF0621_0849 | HMPREF0621_1093 | comF family protein; COG: COG1040; Pfam: PF00156. | Bacterial type II secretion system domain protein F; Pfam: PF00482; InterPro: IPR001992. | 0.448 |
| comF | rec | HMPREF0621_0849 | HMPREF0621_1653 | comF family protein; COG: COG1040; Pfam: PF00156. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.863 |
| dprA | comF | HMPREF0621_0823 | HMPREF0621_0849 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | comF family protein; COG: COG1040; Pfam: PF00156. | 0.908 |
| dprA | pilB | HMPREF0621_0823 | HMPREF0621_1094 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF05157,PF00437; InterPro: IPR001482. | 0.613 |
| dprA | pilC | HMPREF0621_0823 | HMPREF0621_1093 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Bacterial type II secretion system domain protein F; Pfam: PF00482; InterPro: IPR001992. | 0.469 |
| dprA | pilD | HMPREF0621_0823 | HMPREF0621_1092 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | Peptidase, A24 family; Pfam: PF01478; InterPro: IPR000045. | 0.708 |
| dprA | rec | HMPREF0621_0823 | HMPREF0621_1653 | DNA protecting protein DprA; COG: COG0758; Pfam: PF02481; InterPro: IPR003488. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.871 |
| lpxK | EEX49603.1 | HMPREF0621_1651 | HMPREF0621_1650 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | 0.794 |
| lpxK | msbA | HMPREF0621_1651 | HMPREF0621_1652 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.770 |
| lpxK | rec | HMPREF0621_1651 | HMPREF0621_1653 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.713 |
| lpxK | uvrC | HMPREF0621_1651 | HMPREF0621_1648 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.609 |
| msbA | EEX49603.1 | HMPREF0621_1652 | HMPREF0621_1650 | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | Hypothetical protein; Pfam: PF03966; InterPro: IPR005651; 2.7.1.130; Belongs to the UPF0434 family. | 0.616 |
| msbA | lpxK | HMPREF0621_1652 | HMPREF0621_1651 | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.770 |
| msbA | rec | HMPREF0621_1652 | HMPREF0621_1653 | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.804 |