| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49709.1 | exsB | HMPREF0621_1756 | HMPREF0621_1758 | Hypothetical protein. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.414 |
| EEX49709.1 | lysS | HMPREF0621_1756 | HMPREF0621_1755 | Hypothetical protein. | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.486 |
| EEX49709.1 | queD | HMPREF0621_1756 | HMPREF0621_1759 | Hypothetical protein. | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | 0.414 |
| EEX49709.1 | queE | HMPREF0621_1756 | HMPREF0621_1760 | Hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.414 |
| EEX49709.1 | siaB | HMPREF0621_1756 | HMPREF0621_1757 | Hypothetical protein. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.651 |
| cap5G | siaB | HMPREF0621_0375 | HMPREF0621_1757 | UDP-N-acetylglucosamine 2-epimerase; COG: COG0381; Pfam: PF02350; InterPro: IPR003331; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.524 |
| exsB | EEX49709.1 | HMPREF0621_1758 | HMPREF0621_1756 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Hypothetical protein. | 0.414 |
| exsB | queD | HMPREF0621_1758 | HMPREF0621_1759 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | 0.993 |
| exsB | queE | HMPREF0621_1758 | HMPREF0621_1760 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.997 |
| exsB | siaB | HMPREF0621_1758 | HMPREF0621_1757 | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.482 |
| kdsC | siaB | HMPREF0621_1453 | HMPREF0621_1757 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.894 |
| lysS | EEX49709.1 | HMPREF0621_1755 | HMPREF0621_1756 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | Hypothetical protein. | 0.486 |
| lysS | siaB | HMPREF0621_1755 | HMPREF0621_1757 | lysine--tRNA ligase; COG: COG1190; Pfam: PF01336,PF00152; InterPro: IPR002313; Belongs to the class-II aminoacyl-tRNA synthetase family. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.417 |
| pdxB | siaB | HMPREF0621_1519 | HMPREF0621_1757 | 4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.507 |
| queD | EEX49709.1 | HMPREF0621_1759 | HMPREF0621_1756 | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | Hypothetical protein. | 0.414 |
| queD | exsB | HMPREF0621_1759 | HMPREF0621_1758 | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.993 |
| queD | queE | HMPREF0621_1759 | HMPREF0621_1760 | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
| queD | siaB | HMPREF0621_1759 | HMPREF0621_1757 | Queuosine biosynthesis protein QueD; COG: COG0720; Pfam: PF01242; InterPro: IPR007115. | Cytidylyltransferase; COG: COG1083; Pfam: PF02348; InterPro: IPR003329. | 0.482 |
| queE | EEX49709.1 | HMPREF0621_1760 | HMPREF0621_1756 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Hypothetical protein. | 0.414 |
| queE | exsB | HMPREF0621_1760 | HMPREF0621_1758 | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Protein ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.997 |