| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GmhB | metI | HMPREF0621_1855 | HMPREF0621_1857 | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | 0.564 |
| GmhB | metN | HMPREF0621_1855 | HMPREF0621_1856 | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.564 |
| GmhB | metQ | HMPREF0621_1855 | HMPREF0621_1858 | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.485 |
| metH | metQ | HMPREF0621_1057 | HMPREF0621_1858 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.405 |
| metH | metY | HMPREF0621_1057 | HMPREF0621_0948 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; COG: COG2873; Pfam: PF01053; InterPro: IPR006235. | 0.951 |
| metI | GmhB | HMPREF0621_1857 | HMPREF0621_1855 | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | 0.564 |
| metI | metN | HMPREF0621_1857 | HMPREF0621_1856 | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
| metI | metQ | HMPREF0621_1857 | HMPREF0621_1858 | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.999 |
| metN | GmhB | HMPREF0621_1856 | HMPREF0621_1855 | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | 0.564 |
| metN | metI | HMPREF0621_1856 | HMPREF0621_1857 | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | 0.999 |
| metN | metQ | HMPREF0621_1856 | HMPREF0621_1858 | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.998 |
| metQ | GmhB | HMPREF0621_1858 | HMPREF0621_1855 | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | D,D-heptose 1,7-bisphosphate phosphatase; COG: COG0241; Pfam: PF00702; InterPro: IPR004446. | 0.485 |
| metQ | metH | HMPREF0621_1858 | HMPREF0621_1057 | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.405 |
| metQ | metI | HMPREF0621_1858 | HMPREF0621_1857 | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | ABC transporter, permease protein; COG: COG2011; Pfam: PF00528; InterPro: IPR000515. | 0.999 |
| metQ | metN | HMPREF0621_1858 | HMPREF0621_1856 | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.998 |
| metQ | metY | HMPREF0621_1858 | HMPREF0621_0948 | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; COG: COG2873; Pfam: PF01053; InterPro: IPR006235. | 0.621 |
| metY | metH | HMPREF0621_0948 | HMPREF0621_1057 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; COG: COG2873; Pfam: PF01053; InterPro: IPR006235. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.951 |
| metY | metQ | HMPREF0621_0948 | HMPREF0621_1858 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; COG: COG2873; Pfam: PF01053; InterPro: IPR006235. | Lipoprotein, YaeC family; COG: COG1464; Pfam: PF03180; InterPro: IPR004478; Belongs to the nlpA lipoprotein family. | 0.621 |