| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX49522.1 | rfaC | HMPREF0621_1877 | HMPREF0621_1879 | Hypothetical protein; Pfam: PF04314; InterPro: IPR007410. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.578 |
| EEX49522.1 | rfaF | HMPREF0621_1877 | HMPREF0621_1878 | Hypothetical protein; Pfam: PF04314; InterPro: IPR007410. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.578 |
| kdtA | rfaC | HMPREF0621_0572 | HMPREF0621_1879 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.935 |
| kdtA | rfaF | HMPREF0621_0572 | HMPREF0621_1878 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.945 |
| rfaC | EEX49522.1 | HMPREF0621_1879 | HMPREF0621_1877 | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | Hypothetical protein; Pfam: PF04314; InterPro: IPR007410. | 0.578 |
| rfaC | kdtA | HMPREF0621_1879 | HMPREF0621_0572 | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.935 |
| rfaC | rfaD | HMPREF0621_1879 | HMPREF0621_0657 | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.540 |
| rfaC | rfaE | HMPREF0621_1879 | HMPREF0621_1187 | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.648 |
| rfaC | rfaF | HMPREF0621_1879 | HMPREF0621_1878 | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.996 |
| rfaD | rfaC | HMPREF0621_0657 | HMPREF0621_1879 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.540 |
| rfaD | rfaE | HMPREF0621_0657 | HMPREF0621_1187 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.976 |
| rfaD | rfaF | HMPREF0621_0657 | HMPREF0621_1878 | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.815 |
| rfaE | rfaC | HMPREF0621_1187 | HMPREF0621_1879 | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.648 |
| rfaE | rfaD | HMPREF0621_1187 | HMPREF0621_0657 | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.976 |
| rfaE | rfaF | HMPREF0621_1187 | HMPREF0621_1878 | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 0.838 |
| rfaF | EEX49522.1 | HMPREF0621_1878 | HMPREF0621_1877 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Hypothetical protein; Pfam: PF04314; InterPro: IPR007410. | 0.578 |
| rfaF | kdtA | HMPREF0621_1878 | HMPREF0621_0572 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.945 |
| rfaF | rfaC | HMPREF0621_1878 | HMPREF0621_1879 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Lipopolysaccharide heptosyltransferase I; COG: COG0859; Pfam: PF01075; InterPro: IPR011908. | 0.996 |
| rfaF | rfaD | HMPREF0621_1878 | HMPREF0621_0657 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.815 |
| rfaF | rfaE | HMPREF0621_1878 | HMPREF0621_1187 | Lipopolysaccharide heptosyltransferase II; COG: COG0859; Pfam: PF01075; InterPro: IPR011910. | Bifunctional protein RfaE, domain I; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.838 |