| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hsrA | mobB | HMPREF0621_1927 | HMPREF0621_1926 | Putative ATP synthase F0, A subunit; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily. | Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435. | 0.778 |
| hsrA | rseA | HMPREF0621_1927 | HMPREF0621_1923 | Putative ATP synthase F0, A subunit; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily. | Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...] | 0.448 |
| hsrA | rseB | HMPREF0621_1927 | HMPREF0621_1924 | Putative ATP synthase F0, A subunit; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily. | MucB/RseB family protein; COG: COG3026; Pfam: PF03888; InterPro: IPR005588. | 0.575 |
| hsrA | rseC | HMPREF0621_1927 | HMPREF0621_1925 | Putative ATP synthase F0, A subunit; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.598 |
| mobB | hsrA | HMPREF0621_1926 | HMPREF0621_1927 | Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435. | Putative ATP synthase F0, A subunit; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily. | 0.778 |
| mobB | rseA | HMPREF0621_1926 | HMPREF0621_1923 | Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435. | Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...] | 0.457 |
| mobB | rseB | HMPREF0621_1926 | HMPREF0621_1924 | Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435. | MucB/RseB family protein; COG: COG3026; Pfam: PF03888; InterPro: IPR005588. | 0.586 |
| mobB | rseC | HMPREF0621_1926 | HMPREF0621_1925 | Molybdopterin-guanine dinucleotide biosynthesis protein B; COG: COG1763; Pfam: PF03205; InterPro: IPR004435. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.613 |
| rnfC | rnfD | HMPREF0621_1200 | HMPREF0621_1199 | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.993 |
| rnfC | rnfG | HMPREF0621_1200 | HMPREF0621_1198 | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.992 |
| rnfC | rseC | HMPREF0621_1200 | HMPREF0621_1925 | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.557 |
| rnfD | rnfC | HMPREF0621_1199 | HMPREF0621_1200 | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.993 |
| rnfD | rnfG | HMPREF0621_1199 | HMPREF0621_1198 | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.994 |
| rnfD | rseC | HMPREF0621_1199 | HMPREF0621_1925 | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.438 |
| rnfG | rnfC | HMPREF0621_1198 | HMPREF0621_1200 | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.992 |
| rnfG | rnfD | HMPREF0621_1198 | HMPREF0621_1199 | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.994 |
| rnfG | rseC | HMPREF0621_1198 | HMPREF0621_1925 | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.502 |
| rpoE | rseA | HMPREF0621_1922 | HMPREF0621_1923 | RNA polymerase sigma factor RpoE; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014286; Belongs to the sigma-70 factor family. ECF subfamily. | Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...] | 0.938 |
| rpoE | rseB | HMPREF0621_1922 | HMPREF0621_1924 | RNA polymerase sigma factor RpoE; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014286; Belongs to the sigma-70 factor family. ECF subfamily. | MucB/RseB family protein; COG: COG3026; Pfam: PF03888; InterPro: IPR005588. | 0.831 |
| rpoE | rseC | HMPREF0621_1922 | HMPREF0621_1925 | RNA polymerase sigma factor RpoE; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014286; Belongs to the sigma-70 factor family. ECF subfamily. | Positive regulator of sigma(E), RseC/MucC; COG: COG3086; Pfam: PF04246; InterPro: IPR007359. | 0.586 |