node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFE95368.1 | EFE98087.1 | HMPREF0758_3059 | HMPREF0758_0132 | Hypothetical protein; COG: COG3122. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.696 |
EFE98087.1 | EFE95368.1 | HMPREF0758_0132 | HMPREF0758_3059 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | Hypothetical protein; COG: COG3122. | 0.696 |
EFE98087.1 | LolD_1 | HMPREF0758_0132 | HMPREF0758_0133 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | ABC transporter, ATP-binding protein; COG: COG4181; Pfam: PF00005; InterPro: IPR003439. | 0.864 |
EFE98087.1 | Sdh_1 | HMPREF0758_0132 | HMPREF0758_0135 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.522 |
EFE98087.1 | arnE | HMPREF0758_0132 | HMPREF0758_3966 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | 0.472 |
EFE98087.1 | lolD | HMPREF0758_0132 | HMPREF0758_4166 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.409 |
EFE98087.1 | macB | HMPREF0758_0132 | HMPREF0758_4460 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.681 |
EFE98087.1 | tesA | HMPREF0758_0132 | HMPREF0758_0134 | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | GDSL-like protein; COG: COG2755; Pfam: PF00657; InterPro: IPR013831. | 0.906 |
LolD_1 | EFE98087.1 | HMPREF0758_0133 | HMPREF0758_0132 | ABC transporter, ATP-binding protein; COG: COG4181; Pfam: PF00005; InterPro: IPR003439. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.864 |
LolD_1 | Sdh_1 | HMPREF0758_0133 | HMPREF0758_0135 | ABC transporter, ATP-binding protein; COG: COG4181; Pfam: PF00005; InterPro: IPR003439. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.517 |
LolD_1 | tesA | HMPREF0758_0133 | HMPREF0758_0134 | ABC transporter, ATP-binding protein; COG: COG4181; Pfam: PF00005; InterPro: IPR003439. | GDSL-like protein; COG: COG2755; Pfam: PF00657; InterPro: IPR013831. | 0.771 |
Sdh_1 | EFE98087.1 | HMPREF0758_0135 | HMPREF0758_0132 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.522 |
Sdh_1 | LolD_1 | HMPREF0758_0135 | HMPREF0758_0133 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | ABC transporter, ATP-binding protein; COG: COG4181; Pfam: PF00005; InterPro: IPR003439. | 0.517 |
Sdh_1 | tesA | HMPREF0758_0135 | HMPREF0758_0134 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | GDSL-like protein; COG: COG2755; Pfam: PF00657; InterPro: IPR013831. | 0.790 |
arnE | EFE98087.1 | HMPREF0758_3966 | HMPREF0758_0132 | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.472 |
arnE | macB | HMPREF0758_3966 | HMPREF0758_4460 | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.402 |
lolD | EFE98087.1 | HMPREF0758_4166 | HMPREF0758_0132 | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.409 |
lolD | macB | HMPREF0758_4166 | HMPREF0758_4460 | Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.823 |
macB | EFE98087.1 | HMPREF0758_4460 | HMPREF0758_0132 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Efflux ABC transporter, permease protein; COG: COG3127; Pfam: PF02687; InterPro: IPR003838. | 0.681 |
macB | arnE | HMPREF0758_4460 | HMPREF0758_3966 | ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | 0.402 |