| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BcsB | glnB | HMPREF0758_1496 | HMPREF0758_0186 | Bacterial cellulose synthase subunit; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.471 |
| BcsB | glnB2 | HMPREF0758_1496 | HMPREF0758_2476 | Bacterial cellulose synthase subunit; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.471 |
| BcsB | gltB | HMPREF0758_1496 | HMPREF0758_1877 | Bacterial cellulose synthase subunit; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.405 |
| amt | glnB | HMPREF0758_0185 | HMPREF0758_0186 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.999 |
| amt | glnB2 | HMPREF0758_0185 | HMPREF0758_2476 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.997 |
| amt | glnD | HMPREF0758_0185 | HMPREF0758_2327 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.543 |
| amt | glnL | HMPREF0758_0185 | HMPREF0758_1298 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG3852; Pfam: PF00989,PF00512,PF02518; InterPro: IPR003594. | 0.810 |
| amt | gltB | HMPREF0758_0185 | HMPREF0758_1877 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.808 |
| amt | nadE | HMPREF0758_0185 | HMPREF0758_2475 | Ammonium transporter; COG: COG0004; Pfam: PF00909; InterPro: IPR001905. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.572 |
| argA | argB | HMPREF0758_2307 | HMPREF0758_1154 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | 0.993 |
| argA | glnB | HMPREF0758_2307 | HMPREF0758_0186 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.693 |
| argA | glnB2 | HMPREF0758_2307 | HMPREF0758_2476 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.693 |
| argA | gltB | HMPREF0758_2307 | HMPREF0758_1877 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.667 |
| argA | purL | HMPREF0758_2307 | HMPREF0758_2470 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.648 |
| argB | argA | HMPREF0758_1154 | HMPREF0758_2307 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | 0.993 |
| argB | glnB | HMPREF0758_1154 | HMPREF0758_0186 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.669 |
| argB | glnB2 | HMPREF0758_1154 | HMPREF0758_2476 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | 0.669 |
| argB | gltB | HMPREF0758_1154 | HMPREF0758_1877 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.654 |
| argB | purL | HMPREF0758_1154 | HMPREF0758_2470 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.410 |
| glnB | BcsB | HMPREF0758_0186 | HMPREF0758_1496 | Nitrogen regulatory protein P-II; COG: COG0347; Pfam: PF00543; InterPro: IPR015867; Belongs to the P(II) protein family. | Bacterial cellulose synthase subunit; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. | 0.471 |