| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FadM | cof | HMPREF0758_0195 | HMPREF0758_0191 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | Cof-like hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P). | 0.473 |
| FadM | fabD | HMPREF0758_0195 | HMPREF0758_4188 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227. | 0.497 |
| FadM | fadB | HMPREF0758_0195 | HMPREF0758_1645 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.424 |
| FadM | fadH | HMPREF0758_0195 | HMPREF0758_1911 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.409 |
| FadM | topA | HMPREF0758_0195 | HMPREF0758_0196 | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | 0.484 |
| cof | FadM | HMPREF0758_0191 | HMPREF0758_0195 | Cof-like hydrolase; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P). | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | 0.473 |
| fabD | FadM | HMPREF0758_4188 | HMPREF0758_0195 | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227. | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | 0.497 |
| fabD | fadB | HMPREF0758_4188 | HMPREF0758_1645 | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.638 |
| fadB | FadM | HMPREF0758_1645 | HMPREF0758_0195 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | 0.424 |
| fadB | fabD | HMPREF0758_1645 | HMPREF0758_4188 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR001227. | 0.638 |
| fadB | fadH | HMPREF0758_1645 | HMPREF0758_1911 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | 0.804 |
| fadH | FadM | HMPREF0758_1911 | HMPREF0758_0195 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | 0.409 |
| fadH | fadB | HMPREF0758_1911 | HMPREF0758_1645 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.804 |
| topA | FadM | HMPREF0758_0196 | HMPREF0758_0195 | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | acyl-CoA thioester hydrolase, YbgC/YbaW family; COG: COG0824; Pfam: PF03061; InterPro: IPR006684. | 0.484 |